Despite important advances in the treatment of learning disabilities (LDs), the dominant approach to intervention?direct skills instruction?fails to meet the needs of 25-40% of LD students. This, combined with the heterogeneity of LDs, indicates the need to expand the framework for LD treatment with innovative approaches that target the specific needs of subgroups of LD students. This study addresses a subset of the LD population with a distinctive set of needs: students with comorbid difficulty across word reading & calculations. This LD subgroup experiences weaker outcomes in both reading & math and poorer response to reading & math treatment than do peers with difficulty in just 1 of these domains. This study is guided by an innovative Theoretical Framework, which identifies opportunities for strengthening early word reading & calculations in theoretically coordinated fashion for this understudied and underserved population.
The aim of this Phase 1/2 Clinical Trial is to extend understanding about connections between early reading & math and investigate the mechanisms by which effects of coordinated treatment may occur (Phase 1) while also assessing short-term effects of coordinated treatment (Phase 2). Comorbid 1st-grade students are randomly assigned to 4 conditions, a control group, coordinated treatment across reading & math, reading-only treatment, & math-only treatment. We (1) test coordinated treatment?s short-term effects on reading & math outcomes, while assessing (2) whether improved reading skill serves as a mediator of coordinated treatment?s effects on math outcomes and whether improved math skill serves as a mediator of coordinated treatment?s effects on reading outcomes; (3) whether improvement in targeted cognitive processes mediates coordinated treatment?s effects on reading & math outcomes in similar ways; & (4) whether other associated cognitive processes moderate coordinated treatment?s effects on reading & math outcomes in similar ways. This study impacts science by deepening understanding about connections between early reading & math development and offering insights to guide future directions for accelerating the learning of students with these comorbid LDs. This study impacts clinical practice by addressing word-reading + calculations comorbid LDs in a theoretically coordinated manner, which should ease the logistical challenges schools face in providing multiple forms of intervention to students with comorbidity ? challenges that often mean these children do not receive treatment in both domains. The focus is highly relevant & significant because comorbid reading & math LDs are associated with long-term negative consequences, including problems with employment, health, social adjustment, & quality of life.

Public Health Relevance

Word-reading (WR) is foundational to text comprehension, and calculations (CA) are foundational to higher- level math, such as word problems, fractions, and algebra. A learning disability (LD) in either domain undermines school achievement, quality of life, & financial security. Yet, LDs that span WR & CA are common; are inadequately researched & poorly understood; result in worse outcomes than does difficulty in just one of these domains; and thus are a serious and understudied public health problem.

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Research Project (R01)
Project #
5R01HD097772-02
Application #
10011936
Study Section
Child Psychopathology and Developmental Disabilities Study Section (CPDD)
Program Officer
Miller, Brett
Project Start
2019-09-06
Project End
2024-06-30
Budget Start
2020-07-01
Budget End
2021-06-30
Support Year
2
Fiscal Year
2020
Total Cost
Indirect Cost
Name
Vanderbilt University Medical Center
Department
Psychology
Type
Schools of Education
DUNS #
965717143
City
Nashville
State
TN
Country
United States
Zip Code
37203