The goal of the Gene Ontology (GO) consortium is to provide shared, structured vocabularies for the biological description of gene products in any organism. This work includes building three extensive ontologies; those for molecular function, biological process and cellular components. These terms will be used to annotate gene products in databases of the consortium members. Further, a repository database and public Web pages will be created to allow querying for these terms across annotated datasets provided by the model organism databases. The GO consortium, initiated in 1998, is currently a collaboration among three model organism databases: FlyBase, the Saccharomyces Genome Database (SGD), and the Mouse Genome Informatics databases (MGD/GXD). It is our intention for this consortium to be joined by others who are annotating attributes of gene products for other species.

Agency
National Institute of Health (NIH)
Institute
National Human Genome Research Institute (NHGRI)
Type
Research Project (R01)
Project #
3R01HG002273-01S1
Application #
6488124
Study Section
Genome Study Section (GNM)
Program Officer
Peterson, Jane
Project Start
2001-01-19
Project End
2003-12-31
Budget Start
2001-08-24
Budget End
2001-12-31
Support Year
1
Fiscal Year
2001
Total Cost
$42,675
Indirect Cost
Name
Jackson Laboratory
Department
Type
DUNS #
042140483
City
Bar Harbor
State
ME
Country
United States
Zip Code
04609
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Drabkin, Harold J; Blake, Judith A; Mouse Genome Informatics Database (2012) Manual Gene Ontology annotation workflow at the Mouse Genome Informatics Database. Database (Oxford) 2012:bas045
Diehl, Alexander D; Augustine, Alison Deckhut; Blake, Judith A et al. (2011) Hematopoietic cell types: prototype for a revised cell ontology. J Biomed Inform 44:75-9
Alam-Faruque, Yasmin; Huntley, Rachael P; Khodiyar, Varsha K et al. (2011) The impact of focused Gene Ontology curation of specific mammalian systems. PLoS One 6:e27541

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