Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL014461-13S1
Application #
3334771
Study Section
Cardiovascular and Pulmonary Research B Study Section (CVB)
Project Start
1974-09-01
Project End
1986-03-31
Budget Start
1985-12-01
Budget End
1986-03-31
Support Year
13
Fiscal Year
1986
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Williamson, J R; Monck, J R (1990) Signal transduction mechanisms involved in hormonal Ca2+ fluxes. Environ Health Perspect 84:121-36
Hansen, C A; Monck, J R; Williamson, J R (1990) Measurement of intracellular free calcium to investigate receptor-mediated calcium signaling. Methods Enzymol 191:691-706
Monck, J R; Williamson, R E; Rogulja, I et al. (1990) Angiotensin II effects on the cytosolic free Ca2+ concentration in N1E-115 neuroblastoma cells: kinetic properties of the Ca2+ transient measured in single fura-2-loaded cells. J Neurochem 54:278-87
Joseph, S K; Hansen, C A; Williamson, J R (1989) Inositol tetrakisphosphate mobilizes calcium from cerebellum microsomes. Mol Pharmacol 36:391-7
Joseph, S K; Williamson, J R (1989) Inositol polyphosphates and intracellular calcium release. Arch Biochem Biophys 273:1-15
Williamson, J R; Monck, J R (1989) Hormone effects on cellular Ca2+ fluxes. Annu Rev Physiol 51:107-24
Bjornsson, O G; Monck, J R; Williamson, J R (1989) Identification of P2Y purinoceptors associated with voltage-activated cation channels in cardiac ventricular myocytes of the rat. Eur J Biochem 186:395-404
Bjornsson, O G; Williamson, J R (1988) Prolonged suppression of coronary flow rate and cardiac work induced by leukotriene D4, and the reversal of this effect by activators of adenylate cyclase. Ann N Y Acad Sci 524:75-90
Bjornsson, O G; Kobayashi, K; Williamson, J R (1988) Modulation of coronary flow rate and cardiac contractility by the divalent cation ionophore A23187 and inhibitors of the cyclooxygenase and 5-lipoxygenase pathways: development of heterogeneous patterns of myocardial ischemia. Naunyn Schmiedebergs Arch Pharmacol 337:191-202
Johanson, R A; Hansen, C A; Williamson, J R (1988) Purification of D-myo-inositol 1,4,5-trisphosphate 3-kinase from rat brain. J Biol Chem 263:7465-71

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