Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL023240-15
Application #
2215645
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1978-07-01
Project End
1997-03-31
Budget Start
1994-04-01
Budget End
1997-03-31
Support Year
15
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Szymanski, P T; Ferguson, D G; Paul, R J (2002) Polylysine binding to unphosphorylated smooth muscle myosin enhances formation and stabilizes myosin filaments in vitro. Acta Physiol Scand 174:337-46
Shimizu, S; Bowman, P S; Thorne 3rd, G et al. (2000) Effects of hypoxia on isometric force, intracellular Ca(2+), pH, and energetics in porcine coronary artery. Circ Res 86:862-70
Shimizu, S; Paul, R J (1999) Hypoxia and alkalinization inhibit endothelium-derived nitric oxide but not endothelium-derived hyperpolarizing factor responses in porcine coronary artery. J Pharmacol Exp Ther 291:335-44
Tosun, M; Paul, R J; Rapoport, R M (1998) Role of extracellular Ca++ influx via L-type and non-L-type Ca++ channels in thromboxane A2 receptor-mediated contraction in rat aorta. J Pharmacol Exp Ther 284:921-8
Foy, R A; Shimizu, S; Paul, R J (1997) The effects of hypoxia on pHi in porcine coronary artery endothelium and smooth muscle. A novel method for measurements in endothelial cells in situ. Circ Res 80:21-7
Wingard, C J; Paul, R J; Murphy, R A (1997) Energetic cost of activation processes during contraction of swine arterial smooth muscle. J Physiol 501 ( Pt 1):213-23
Liu, L H; Paul, R J; Sutliff, R L et al. (1997) Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3. J Biol Chem 272:30538-45
Lorenz, J N; Paul, R J (1997) Dependence of Ca2+ channel currents on endogenous and exogenous sources of ATP in portal vein smooth muscle. Am J Physiol 272:H987-94
Shimizu, S; Shimizu, K; Paul, R J (1997) Cold storage induces an endothelium-independent relaxation to hypoxia/reoxygenation in porcine coronary arteries. J Vasc Res 34:399-407
Obara, K; Bowman, P S; Ishida, Y et al. (1997) Effects of hypoxia on [Ca2+]i, pHi and myosin light chain phosphorylation in guinea-pig taenia caeci. J Physiol 503 ( Pt 2):427-33

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