Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL026873-16
Application #
2216033
Study Section
Biophysical Chemistry Study Section (BBCB)
Project Start
1981-05-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Diego
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
077758407
City
La Jolla
State
CA
Country
United States
Zip Code
92093
Doolittle, Russell F (2003) Some notes on crystallizing fibrinogen and fibrin fragments. Biophys Chem 100:307-13
Doolittle, Russell F (2003) Structural basis of the fibrinogen-fibrin transformation: contributions from X-ray crystallography. Blood Rev 17:33-41
Jiang, Yong; Doolittle, Russell F (2003) The evolution of vertebrate blood coagulation as viewed from a comparison of puffer fish and sea squirt genomes. Proc Natl Acad Sci U S A 100:7527-32
Doolittle, R F (2003) X-ray crystallographic studies on fibrinogen and fibrin. J Thromb Haemost 1:1559-65
Yang, Zhe; Pandi, Leela; Doolittle, Russell F (2002) The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface. Biochemistry 41:15610-7
Yang, Zhe; Spraggon, Glen; Pandi, Leela et al. (2002) Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide. Biochemistry 41:10218-24
Yang, Z; Kollman, J M; Pandi, L et al. (2001) Crystal structure of native chicken fibrinogen at 2.7 A resolution. Biochemistry 40:12515-23
Yang, Z; Mochalkin, I; Doolittle, R F (2000) A model of fibrin formation based on crystal structures of fibrinogen and fibrin fragments complexed with synthetic peptides. Proc Natl Acad Sci U S A 97:14156-61
Yang, Z; Mochalkin, I; Veerapandian, L et al. (2000) Crystal structure of native chicken fibrinogen at 5.5-A resolution. Proc Natl Acad Sci U S A 97:3907-12
Lin, Y C; Doolittle, R F (2000) A latent inhibitor of fibrin polymerization with ancillary anticoagulant activity. Thromb Res 97:375-8

Showing the most recent 10 out of 33 publications