Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL027016-18A1S1
Application #
2822491
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1981-07-01
Project End
2002-08-31
Budget Start
1998-07-01
Budget End
1998-08-31
Support Year
18
Fiscal Year
1998
Total Cost
Indirect Cost
Name
University of Illinois at Chicago
Department
Pharmacology
Type
Schools of Medicine
DUNS #
121911077
City
Chicago
State
IL
Country
United States
Zip Code
60612
Minshall, Richard D; Vandenbroucke, Emily E; Holinstat, Michael et al. (2010) Role of protein kinase Czeta in thrombin-induced RhoA activation and inter-endothelial gap formation of human dermal microvessel endothelial cell monolayers. Microvasc Res 80:240-9
Fan, Jie; Malik, Asrar B (2003) Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors. Nat Med 9:315-21
Ong, Evan S; Gao, Xiao-Pei; Xu, Ning et al. (2003) E. coli pneumonia induces CD18-independent airway neutrophil migration in the absence of increased lung vascular permeability. Am J Physiol Lung Cell Mol Physiol 285:L879-88
Fan, Jie; Frey, Randall S; Malik, Asrar B (2003) TLR4 signaling induces TLR2 expression in endothelial cells via neutrophil NADPH oxidase. J Clin Invest 112:1234-43
Mehta, Dolly; Tiruppathi, Chinnaswamy; Sandoval, Raudal et al. (2002) Modulatory role of focal adhesion kinase in regulating human pulmonary arterial endothelial barrier function. J Physiol 539:779-89
Frey, Randall S; Rahman, Arshad; Kefer, John C et al. (2002) PKCzeta regulates TNF-alpha-induced activation of NADPH oxidase in endothelial cells. Circ Res 90:1012-9
Fan, Jie; Frey, Randall S; Rahman, Arshad et al. (2002) Role of neutrophil NADPH oxidase in the mechanism of tumor necrosis factor-alpha -induced NF-kappa B activation and intercellular adhesion molecule-1 expression in endothelial cells. J Biol Chem 277:3404-11
Mehta, D; Rahman, A; Malik, A B (2001) Protein kinase C-alpha signals rho-guanine nucleotide dissociation inhibitor phosphorylation and rho activation and regulates the endothelial cell barrier function. J Biol Chem 276:22614-20
Kefer, J; Rahman, A; Anwar, K N et al. (2001) Decreased oxidant buffering impairs NF-kappaB activation and ICAM-1 transcription in endothelial cells. Shock 15:11-5
Rahman, A; Anwar, K N; Uddin, S et al. (2001) Protein kinase C-delta regulates thrombin-induced ICAM-1 gene expression in endothelial cells via activation of p38 mitogen-activated protein kinase. Mol Cell Biol 21:5554-65

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