In New Mexico, Hispanic male mortality rates for lung cancer and for chronic obstructive pulmonary disease are markedly lower than rates for non-Hispanic whites. For females, overall rates for Hispanic and non-Hispanic white are similar but the patterns of age-specific rates differ. Cigarette smoking practices may partially explain these differences. To further characterize the epidemiology of respiratory diseases among Hispanics, we have conducted a prevalence survey of residents of Belen, New Mexico. This community, located near Albuquerque, has a stable Hispanic population of approximately 3,900. We have enrolled about 700 Hispanic households, totalling about 2,100 individuals in all age and sex categories. Survey procedures included completion of standard respiratory symptoms questionnaires, a household questionnaire directed at environmental exposures, household and family relationships questionnaires to examine familial aggregation of symptoms and illnesses, spirometry, blood pressure, and measurement of end-tidal carbon monoxide and salivary cotinine. The analyses will be primarily directed at describing the prevalence of respiratory symptoms and diseases in Hispanics; determining risk factors for respiratory disease in this population; and developing prediction equations for spirometric parameters in Hispanics. We obtained a comprehensive cigarette smoking history so that effects of various cigarette types can be compared. The salivary cotinine data will provide a measure of active and passive smoke exposure. The household based design will permit assessment of familial aggregation of respiratory symptoms, diseases, and lung function level. We will examine familial aggregation by calculating inter and intra class correlation coefficients and by using path analysis. We also collected data on non-respiratory diseases, hypertension, diabetes, and gallbladder disease and will be able to compare these data to findings in other populations.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL028120-05
Application #
3339510
Study Section
Epidemiology and Disease Control Subcommittee 3 (EDC)
Project Start
1983-09-30
Project End
1988-08-31
Budget Start
1987-09-01
Budget End
1988-08-31
Support Year
5
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of New Mexico
Department
Type
Schools of Medicine
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Coultas, D B; Stidley, C A; Samet, J M (1993) Cigarette yields of tar and nicotine and markers of exposure to tobacco smoke. Am Rev Respir Dis 148:435-40
Wiggins, C L; Schmidt-Nowara, W W; Coultas, D B et al. (1990) Comparison of self- and spouse reports of snoring and other symptoms associated with sleep apnea syndrome. Sleep 13:245-52
Schmidt-Nowara, W W; Coultas, D B; Wiggins, C et al. (1990) Snoring in a Hispanic-American population. Risk factors and association with hypertension and other morbidity. Arch Intern Med 150:597-601
Samet, J M; Coultas, D B; Howard, C A et al. (1988) Respiratory diseases and cigarette smoking in a Hispanic population in New Mexico. Am Rev Respir Dis 137:815-9
Coultas, D B; Howard, C A; Peake, G T et al. (1988) Discrepancies between self-reported and validated cigarette smoking in a community survey of New Mexico Hispanics. Am Rev Respir Dis 137:810-4
Samet, J M; Coultas, D B; Howard, C A et al. (1988) Diabetes, gallbladder disease, obesity, and hypertension among Hispanics in New Mexico. Am J Epidemiol 128:1302-11
Coultas, D B; Howard, C A; Peake, G T et al. (1987) Salivary cotinine levels and involuntary tobacco smoke exposure in children and adults in New Mexico. Am Rev Respir Dis 136:305-9
Samet, J M (1987) Epidemiologic approaches for the identification of asthma. Chest 91:74S-78S