Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL029837-10
Application #
2216516
Study Section
Metabolism Study Section (MET)
Project Start
1983-04-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Pathology
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Sowden, M P; Collins, H L; Smith, H C et al. (1999) Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase. Biochem J 341 ( Pt 3):639-45
Sparks, J D; Phung, T L; Bolognino, M et al. (1998) Lipoprotein alterations in 10- and 20-week-old Zucker diabetic fatty rats: hyperinsulinemic versus insulinopenic hyperglycemia. Metabolism 47:1315-24
Van Mater, D; Sowden, M P; Cianci, J et al. (1998) Ethanol increases apolipoprotein B mRNA editing in rat primary hepatocytes and McArdle cells. Biochem Biophys Res Commun 252:334-9
Sparks, J D; Collins, H L; Sabio, I et al. (1997) Effects of fatty acids on apolipoprotein B secretion by McArdle RH-7777 rat hepatoma cells. Biochim Biophys Acta 1347:51-61
Phung, T L; Mooney, R A; Kulas, D T et al. (1997) Suppression of the protein tyrosine phosphatase LAR reduces apolipoprotein B secretion by McA-RH7777 rat hepatoma cells. Biochem Biophys Res Commun 237:367-71
Phung, T L; Roncone, A; Jensen, K L et al. (1997) Phosphoinositide 3-kinase activity is necessary for insulin-dependent inhibition of apolipoprotein B secretion by rat hepatocytes and localizes to the endoplasmic reticulum. J Biol Chem 272:30693-702
Phung, T L; Sowden, M P; Sparks, J D et al. (1996) Regulation of hepatic apolipoprotein B RNA editing in the genetically obese Zucker rat. Metabolism 45:1056-8
Sparks, J D; Sparks, C E (1996) Chromatographic method for isolation and quantification of apolipoproteins B-100 and B-48. Methods Enzymol 263:104-20
Schock, D; Kuo, S R; Steinburg, M F et al. (1996) An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editing. Proc Natl Acad Sci U S A 93:1097-102
Sparks, J D; Phung, T L; Bolognino, M et al. (1996) Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes. Biochem J 313 ( Pt 2):567-74

Showing the most recent 10 out of 35 publications