Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL032254-06
Application #
3343584
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1989-07-01
Project End
1990-09-30
Budget Start
1989-07-01
Budget End
1990-09-30
Support Year
6
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Cor Therapeutics, Inc.
Department
Type
DUNS #
City
South San Francisco
State
CA
Country
United States
Zip Code
94080
Parise, L V; Steiner, B; Nannizzi, L et al. (1993) Evidence for novel binding sites on the platelet glycoprotein IIb and IIIa subunits and immobilized fibrinogen. Biochem J 289 ( Pt 2):445-51
Phillips, D R; Fitzgerald, L; Parise, L et al. (1992) Platelet membrane glycoprotein IIb-IIIa complex: purification, characterization, and reconstitution into phospholipid vesicles. Methods Enzymol 215:244-63
Phillips, D R (1992) Surface labeling of platelet membrane glycoproteins. Methods Enzymol 215:412-9
Lanza, F; Wolf, D; Fox, C F et al. (1991) cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins. J Biol Chem 266:10638-45
Steiner, B; Parise, L V; Leung, B et al. (1991) Ca(2+)-dependent structural transitions of the platelet glycoprotein IIb-IIIa complex. Preparation of stable glycoprotein IIb and IIIa monomers. J Biol Chem 266:14986-91
Lanza, F; Kieffer, N; Phillips, D R et al. (1990) Characterization of the human platelet glycoprotein IIIa gene. Comparison with the fibronectin receptor beta-subunit gene. J Biol Chem 265:18098-103
Sosnoski, D M; Emanuel, B S; Hawkins, A L et al. (1988) Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa. J Clin Invest 81:1993-8
Fitzgerald, L A; Phillips, D R (1988) The molecular biology of platelet and endothelial cell adhesion receptors. Prog Clin Biol Res 283:387-418
Phillips, D R; Charo, I F; Parise, L V et al. (1988) The platelet membrane glycoprotein IIb-IIIa complex. Blood 71:831-43
Phillips, D R; Fitzgerald, L A; Charo, I F et al. (1987) The platelet membrane glycoprotein IIb/IIIa complex. Structure, function, and relationship to adhesive protein receptors in nucleated cells. Ann N Y Acad Sci 509:177-87

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