Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL032588-01S1
Application #
3343960
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1984-07-01
Project End
1987-06-30
Budget Start
1984-12-15
Budget End
1985-06-30
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
University of Connecticut
Department
Type
School of Medicine & Dentistry
DUNS #
City
Farmington
State
CT
Country
United States
Zip Code
Chester, D W; Herbette, L G; Mason, R P et al. (1987) Diffusion of dihydropyridine calcium channel antagonists in cardiac sarcolemmal lipid multibilayers. Biophys J 52:1021-30
Rzepecki, L M; Strittmatter, P; Herbette, L G (1986) X-ray diffraction analysis of cytochrome b5 reconstituted in egg phosphatidylcholine vesicles. Biophys J 49:829-38
Colvin, R A; Ashavaid, T F; Herbette, L G (1985) Structure-function studies of canine cardiac sarcolemmal membranes. I. Estimation of receptor site densities. Biochim Biophys Acta 812:601-8
Rhodes, D G; Sarmiento, J G; Herbette, L G (1985) Kinetics of binding of membrane-active drugs to receptor sites. Diffusion-limited rates for a membrane bilayer approach of 1,4-dihydropyridine calcium channel antagonists to their active site. Mol Pharmacol 27:612-23
Blasie, J K; Herbette, L G; Pascolini, D et al. (1985) Time-resolved x-ray diffraction studies of the sarcoplasmic reticulum membrane during active transport. Biophys J 48:9-18
Herbette, L G; MacAlister, T; Ashavaid, T F et al. (1985) Structure-function studies of canine cardiac sarcolemmal membranes. II. Structural organization of the sarcolemmal membrane as determined by electron microscopy and lamellar X-ray diffraction. Biochim Biophys Acta 812:609-23
Katz, A M; Freston, J W; Messineo, F C et al. (1985) Membrane damage and the pathogenesis of cardiomyopathies. J Mol Cell Cardiol 17 Suppl 2:11-20
Herbette, L; DeFoor, P; Fleischer, S et al. (1985) The separate profile structures of the functional calcium pump protein and the phospholipid bilayer within isolated sarcoplasmic reticulum membranes determined by X-ray and neutron diffraction. Biochim Biophys Acta 817:103-22