Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL032853-07S1
Application #
3344374
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1991-07-01
Project End
1994-06-30
Budget Start
1992-07-01
Budget End
1994-06-30
Support Year
7
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
Upstate Medical University
Department
Type
Schools of Medicine
DUNS #
058889106
City
Syracuse
State
NY
Country
United States
Zip Code
13210

  Publications

Finch, C N; Lyle, V A; Cunningham, D et al. (1996) Expression of human platelet glycoprotein Ib beta in insect cells. Thromb Res 81:679-86
Beadling, W V; Herman, J H; Stuart, M J et al. (1995) Fetal bleeding in neonatal alloimmune thrombocytopenia mediated by anti-PlAl is not associated with inhibition of fibrinogen binding to platelet GPIIb/IIIa. Am J Clin Pathol 103:636-41
Pincus, M R; Carty, R P; Miller, J L (1994) Structural implications of the substitution of Val for Met at residue 239 in the alpha chain of human platelet glycoprotein Ib. J Protein Chem 13:629-33
Miller, J L; Lyle, V A; Cunningham, D (1992) Mutation of leucine-57 to phenylalanine in a platelet glycoprotein Ib alpha leucine tandem repeat occurring in patients with an autosomal dominant variant of Bernard-Soulier disease. Blood 79:439-46
Kroll, M H; Mendelsohn, M E; Miller, J L et al. (1992) Monoclonal antibody AG-1 initiates platelet activation by a pathway dependent on glycoprotein IIb-IIIa and extracellular calcium. Biochim Biophys Acta 1137:248-56
Pincus, M R; Dykes, D C; Carty, R P et al. (1991) Conformational energy analysis of the substitution of Val for Gly 233 in a functional region of platelet GPIb alpha in platelet-type von Willebrand disease. Biochim Biophys Acta 1097:133-9
Miller, J L; Cunningham, D; Lyle, V A et al. (1991) Mutation in the gene encoding the alpha chain of platelet glycoprotein Ib in platelet-type von Willebrand disease. Proc Natl Acad Sci U S A 88:4761-5
Kroll, M H; Claure, R E; Miller, J L (1990) The monoclonal antibody AG-1, a potent stimulator of human platelets, interacts with a low molecular weight GTP-binding protein. Biochem Biophys Res Commun 171:1252-7
Finch, C N; Miller, J L; Lyle, V A et al. (1990) Evidence that an abnormality in the glycoprotein Ib alpha gene is not the cause of abnormal platelet function in a family with classic Bernard-Soulier disease. Blood 75:2357-62
Miller, J L; Hustad, K O; Kupinski, J M et al. (1990) Increased platelet sensitivity to ristocetin is predicted by the binding characteristics of a GPIb/IX determinant. Br J Haematol 74:313-9

Showing the most recent 10 out of 15 publications