Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL033337-01
Application #
3345126
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1985-02-01
Project End
1988-01-31
Budget Start
1985-02-01
Budget End
1986-01-31
Support Year
1
Fiscal Year
1985
Total Cost
Indirect Cost
Name
Temple University
Department
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19122
Yang, X; Disa, J; Rao, A K (1992) Guanosine 5'-0-(3-thiotriphosphate) induced calcium release in human platelets is mediated by inositol 1,4,5-triphosphate. Thromb Res 65:549-58
Rao, A K; Kowalska, M A; Disa, J (1989) Impaired cytoplasmic ionized calcium mobilization in inherited platelet secretion defects. Blood 74:664-72
Purdon, A D; Rao, A K (1989) Interaction of albumin, arachidonic acid and prostanoids in platelets. Prostaglandins Leukot Essent Fatty Acids 35:213-8
Rao, A K; Willis, J; Kowalska, M A et al. (1988) Differential requirements for platelet aggregation and inhibition of adenylate cyclase by epinephrine. Studies of a familial platelet alpha 2-adrenergic receptor defect. Blood 71:494-501
Kowalska, M A; Rao, A K; Disa, J (1988) High concentrations of exogenous arachidonate inhibit calcium mobilization in platelets by stimulation of adenylate cyclase. Biochem J 253:255-62
Rao, A K; Schapira, M; Clements, M L et al. (1988) A prospective study of platelets and plasma proteolytic systems during the early stages of Rocky Mountain spotted fever. N Engl J Med 318:1021-8
Barnette, R E; Shupak, R C; Pontius, J et al. (1988) In vitro effect of fresh frozen plasma on the activated coagulation time in patients undergoing cardiopulmonary bypass. Anesth Analg 67:57-60
Annamalai, A E; Rao, A K; Chiu, H C et al. (1987) Epitope mapping of functional domains of human factor Va with human and murine monoclonal antibodies. Evidence for the interaction of heavy chain with factor Xa and calcium. Blood 70:139-46
Rao, A K; Kowalska, M A (1987) ADP-induced platelet shape change and mobilization of cytoplasmic ionized calcium are mediated by distinct binding sites on platelets: 5'-p-fluorosulfonylbenzoyladenosine is a weak platelet agonist. Blood 70:751-6
Day, H J; Rao, A K (1986) Evaluation of platelet function. Semin Hematol 23:89-101

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