Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL033463-02
Application #
3345397
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1984-12-01
Project End
1986-11-30
Budget Start
1985-12-01
Budget End
1986-11-30
Support Year
2
Fiscal Year
1986
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Byrne, J G; Appleyard, R F; Sun, S C et al. (1993) Thromboxane A2 mediates reperfusion injury after heart preservation. J Heart Lung Transplant 12:256-62
Byrne, J G; Appleyard, R F; Sun, S C et al. (1993) Cardiac-derived thromboxane A2. An initiating mediator of reperfusion injury? J Thorac Cardiovasc Surg 105:689-93
Byrne, J G; Appleyard, R F; Lee, C C et al. (1992) Controlled reperfusion of the regionally ischemic myocardium with leukocyte-depleted blood reduces stunning, the no-reflow phenomenon, and infarct size. J Thorac Cardiovasc Surg 103:66-71;discussion 71-2
Sun, S C; Appleyard, R; Masetti, P et al. (1992) Improved recovery of heart transplants by combined use of oxygen-derived free radical scavengers and energy enhancement. J Thorac Cardiovasc Surg 104:830-7
Austin, J C; Berrizbeitia, L D; Schoen, F J et al. (1988) Thromboxane synthetase inhibition reduces ventricular irritability after coronary occlusion and reperfusion. Am Heart J 115:505-9
Melendez, F J; Gharagozloo, F; Sun, S C et al. (1988) Effects of diltiazem cardioplegia on global function, segmental contractility, and the area of necrosis after acute coronary artery occlusion and surgical reperfusion. J Thorac Cardiovasc Surg 95:613-7
Gharagozloo, F; Melendez, F J; Hein, R A et al. (1988) The effect of oxygen free radical scavengers on the recovery of regional myocardial function after acute coronary occlusion and surgical reperfusion. J Thorac Cardiovasc Surg 95:631-6
Gharagozloo, F; Melendez, F J; Hein, R A et al. (1988) The effect of superoxide dismutase and catalase on the extended preservation of the ex vivo heart for transplantation. J Thorac Cardiovasc Surg 95:1008-13
Gharagozloo, F; Cohn, L H (1987) Measurement of coronary blood flow: a critical review. J Surg Res 42:314-27
Gharagozloo, F; Melendez, F J; Hein, R A et al. (1987) The effect of amino acid L-glutamate on the extended preservation ex vivo of the heart for transplantation. Circulation 76:V65-70

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