Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL033629-07S1
Application #
3345706
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1991-07-01
Project End
1993-06-30
Budget Start
1991-07-01
Budget End
1993-06-30
Support Year
7
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Fronticelli, C; Brinigar, W S; Olson, J S et al. (1993) Recombinant human hemoglobin: modification of the polarity of the beta-heme pocket by a valine67(E11)-->threonine mutation. Biochemistry 32:1235-42
Gryczynski, Z; Bucci, E; Kuyyba, J (1993) Linear dichroism study of metalloporphyrin transition moments in view of radiationless interactions with tryptophan in hemoproteins. Photochem Photobiol 58:492-8
Bucci, E; Fronticelli, C; Gryczynski, Z et al. (1993) Effect of intramolecular cross-links on the enthalpy and quaternary structure of the intermediates of oxygenation of human hemoglobin. Biochemistry 32:3519-26
Gryczynski, Z; Bucci, E (1993) A new front-face optical cell for measuring weak fluorescent emissions with time resolution in the picosecond time scale. Biophys Chem 48:31-8
Chiancone, E; Fronticelli, C; Gattoni, M et al. (1992) Immobilized hemoglobin in the purification of hemoglobin-based oxygen carriers. J Chromatogr 604:117-23
Bucci, E; Fronticelli, C; Razynska, A et al. (1992) Hemoglobin tetramers stabilized with polyaspirins. Biomater Artif Cells Immobilization Biotechnol 20:243-52
Gryczynski, Z; Tenenholz, T; Bucci, E (1992) Rates of energy transfer between tryptophans and hemes in hemoglobin, assuming that the heme is a planar oscillator. Biophys J 63:648-53
Urbaitis, B K; Razynska, A; Corteza, Q et al. (1991) Intravascular retention and renal handling of purified natural and intramolecularly cross-linked hemoglobins. J Lab Clin Med 117:115-21
Razynska, A; Fronticelli, C; Di Cera, E et al. (1990) Effect of temperature on oxygen affinity and anion binding of bovine hemoglobin. Biophys Chem 38:111-5
Bucci, E; Steiner, R F (1990) Perturbation of molecular species distribution in steady states supported by a flow of energy. Models analogous to Ca2(+)-dependent ATPase and phosphorylase b. Biophys Chem 37:61-71

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