Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL033709-09
Application #
2217314
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1984-07-01
Project End
1996-11-30
Budget Start
1996-06-01
Budget End
1996-11-30
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Miami School of Medicine
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Zhang-Hoover, J; Sutton, A; Stein-Streilein, J (2001) CD40/CD40 ligand interactions are critical for elicitation of autoimmune-mediated fibrosis in the lung. J Immunol 166:3556-63
Stein-Streilein, J; Sonoda, K H; Faunce, D et al. (2000) Regulation of adaptive immune responses by innate cells expressing NK markers and antigen-transporting macrophages. J Leukoc Biol 67:488-94
Asea, A; Stein-Streilein, J (1998) Signalling through NK1.1 triggers NK cells to die but induces NK T cells to produce interleukin-4. Immunology 93:296-305
D'Orazio, J A; Cole, B C; Stein-Streilein, J (1996) Mycoplasma arthritidis mitogen up-regulates human NK cell activity. Infect Immun 64:441-7
Hu, H; Stein-Streilein, J (1993) Hapten-immune pulmonary interstitial fibrosis (HIPIF) in mice requires both CD4+ and CD8+ T lymphocytes. J Leukoc Biol 54:414-22
Stein-Streilein, J; Salter-Cid, L; Roberts, B et al. (1992) Persistent pulmonary interstitial fibrosis, induced by immune response to TNP, is associated with altered mRNA procollagen type I:III ratio. Reg Immunol 4:391-400
Kimura, R; Hu, H; Stein-Streilein, J (1992) Delayed-type hypersensitivity responses regulate collagen deposition in the lung. Immunology 77:550-5
Kimura, R; Hu, H; Stein-Streilein, J (1992) Immunological tolerance to hapten prevents subsequent induction of hapten-immune pulmonary interstitial fibrosis (HIPIF). Cell Immunol 145:351-8
Garcia, H; Salter-Cid, L; Stein-Streilein, J (1992) Persistent interleukin-2 activity and molecular evidence for expression of lymphotoxin in the hapten-immune model for pulmonary interstitial fibrosis. Am J Respir Cell Mol Biol 6:22-8
Peacock, J S; Tan, J; Guffee, J et al. (1991) Monovalent Fab fragments of D7.5 monoclonal antibody activate intracellular Ca2+ mobilization and secretion of cytolytic factors by thymus cells. J Leukoc Biol 49:90-7

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