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Kerrigan, J E; Powers, J C; VanDerveer, D (1996) 4-Chloro-7-(iodoacetyl)amino-3-methoxy-isocoumarin. Acta Crystallogr C 52 ( Pt 2):451-3
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Kam, C M; Hernandez, M A; Patil, G S et al. (1995) Mammalian tissue trypsin-like enzymes: substrate specificity and inhibitory potency of substituted isocoumarin mechanism-based inhibitors, benzamidine derivatives, and arginine fluoroalkyl ketone transition-state inhibitors. Arch Biochem Biophys 316:808-14
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Powers, J C; Kam, C M (1995) Peptide thioester substrates for serine peptidases and metalloendopeptidases. Methods Enzymol 248:3-18
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Kerrigan, J E; Oleksyszyn, J; Kam, C M et al. (1995) Mechanism-based isocoumarin inhibitors for human leukocyte elastase. Effect of the 7-amino substituent and 3-alkoxy group in 3-alkoxy-7-amino-4-chloroisocoumarins on inhibitory potency. J Med Chem 38:544-52
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Brown, A D; Powers, J C (1995) Rates of thrombin acylation and deacylation upon reaction with low molecular weight acylating agents, carbamylating agents and carbonylating agents. Bioorg Med Chem 3:1091-7
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Oleksyszyn, J; Powers, J C (1994) Amino acid and peptide phosphonate derivatives as specific inhibitors of serine peptidases. Methods Enzymol 244:423-41
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Powers, J C; Kam, C M (1994) Isocoumarin inhibitors of serine peptidases. Methods Enzymol 244:442-57
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Kam, C M; Kerrigan, J E; Plaskon, R R et al. (1994) Mechanism-based isocoumarin inhibitors for blood coagulation serine proteases. Effect of the 7-substituent in 7-amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on inhibitory and anticoagulant potency. J Med Chem 37:1298-306
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Dolman, K M; van de Wiel, B A; Kam, C M et al. (1993) Proteinase 3: substrate specificity and possible pathogenetic effect of Wegener's granulomatosis autoantibodies (c-ANCA) by dysregulation of the enzyme. Adv Exp Med Biol 336:55-60
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