This proposal seeks to study weight maintenance behaviors, weight trends and behavorial differences between healthy, normal weight (+-15 percent IBW) and mildly obese (greater than 20 percent but less than 40 percent IBW) adults retrospectively by history and prospectively over 5 years. Effects on overall health, particularly cardiovascular disease risk (CVD), will be assessed and the characterization of behaviors to formulate predictive models on which to build future interventions will be emphasized. A 2 x 2 x 5, multifactorial design will be used where sex (males vs. females) and weight (obese vs. normal) will be crossed with 5 different age groups according to decades (20-29, 30-39, 40-49, 50-59 and 60+ years), respectively. A longitudinal, process-analysis approach will be utilized where 500 subjects will be studied in their natural setting and followed yearly for 5 years. The selection of subjects will be biased toward the working class (faculty, employees, students and their spouses/friends) reportedly in good health (less than 1 sick day/month for the last year), who will be paid for their participation in the study. A total of 50 (25 normal + 25 obese) will be recruited for each age/sex group. Dependent variables will be: 1) weight (weight trends, fluctuations, interrelationships, body composition); 2) diet (adequacy, eating patterns, caloric balance, varability in nutrient intake, validity of self-reports); 3) activity/exercise (frequency, duration, type, patterns, caloric equivalents, behavioral correlates); 4) behaviors, (weight maintenance, weight gain/loss, adaptive responses); 5) general well-being (days sick and days missed from work, psychopathology (SCL-90R), emotional states (GWB, CES-D), locus of control (Levenson) and routine blood and urinalyses; and 6) CVD risk (lipid profile, BP, 24-hour urinary Na, K, Ca and P, diet, and changes in medical status/medication use). The major data analyses will employ repeated measures, multiple analysis of variance and covariance. Emphasis will also be placed on descriptive analyses and correlational statistics. Overall, this study will provide valuable information regarding behavioral correlates and strategies used for weight maintenance in the prevention of obesity in normal weight individuals and identify strategies which might be successful in the prevention of the progressive escalation and/or extreme fluctuations in weight in the obese state. Medical, nutritional and psychological consequences will also be identified and methodology to be used in future studies will be validated.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL034589-03
Application #
3347631
Study Section
Behavioral Medicine Study Section (BEM)
Project Start
1985-09-30
Project End
1990-09-29
Budget Start
1987-09-30
Budget End
1988-09-29
Support Year
3
Fiscal Year
1987
Total Cost
Indirect Cost
Name
University of Nevada Reno
Department
Type
Schools of Medicine
DUNS #
146515460
City
Reno
State
NV
Country
United States
Zip Code
89557
Suminski, Richard R; Poston, Walker S C; Foreyt, John P et al. (2008) Physical activity assessed with three different methods and the Framingham Risk Score on 10-year coronary heart disease risk. Med Sci Monit 14:CR1-9
Terre, Lisa; Poston, Walker S Carlos; Foreyt, John et al. (2003) Do somatic complaints predict subsequent symptoms of depression? Psychother Psychosom 72:261-7
St Jeor, Sachiko T; Perumean-Chaney, Suzanne; Sigman-Grant, Madeleine et al. (2002) Family-based interventions for the treatment of childhood obesity. J Am Diet Assoc 102:640-4
Shinn, E H; Poston, W S; Kimball, K T et al. (2001) Blood pressure and symptoms of depression and anxiety: a prospective study. Am J Hypertens 14:660-4
McReynolds, P; Altrocchi, J; House, C (2000) Self-pluralism: assessment and relations to adjustment, life changes, and age. J Pers 68:347-81
Katz, D L; Brunner, R L; St Jeor, S T et al. (1998) Dietary fat consumption in a cohort of American adults, 1985-1991: covariates, secular trends, and compliance with guidelines. Am J Health Promot 12:382-90
St Jeor, S T; Brunner, R L; Harrington, M E et al. (1997) A classification system to evaluate weight maintainers, gainers, and losers. J Am Diet Assoc 97:481-8
Foreyt, J P; Brunner, R L; Goodrick, G K et al. (1995) Psychological correlates of weight fluctuation. Int J Eat Disord 17:263-75
Foreyt, J P; Brunner, R L; Goodrick, G K et al. (1995) Psychological correlates of reported physical activity in normal-weight and obese adults: the Reno diet-heart study. Int J Obes Relat Metab Disord 19 Suppl 4:S69-72
Carmody, T P; Brunner, R L; St Jeor, S T (1995) Dietary helplessness and disinhibition in weight cyclers and maintainers. Int J Eat Disord 18:247-56

Showing the most recent 10 out of 15 publications