Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL036255-02
Application #
3351084
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1987-05-01
Project End
1990-04-30
Budget Start
1988-05-01
Budget End
1989-04-30
Support Year
2
Fiscal Year
1988
Total Cost
Indirect Cost
Name
San Francisco State University
Department
Type
Schools of Arts and Sciences
DUNS #
City
San Francisco
State
CA
Country
United States
Zip Code
94132
Chiu, D T; Huang, T Y; Hung, I J et al. (1997) Hemin-induced membrane sulfhydryl oxidation: possible involvement of thiyl radicals. Free Radic Res 27:55-62
Chiu, D T; van den Berg, J; Kuypers, F A et al. (1996) Correlation of membrane lipid peroxidation with oxidation of hemoglobin variants: possibly related to the rates of hemin release. Free Radic Biol Med 21:89-95
Chiu, D T; Zuo, L; Chao, L et al. (1993) Molecular characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency in patients of Chinese descent and identification of new base substitutions in the human G6PD gene. Blood 81:2150-4
Chiu, D T; Lai, K M; Xu, C M et al. (1993) Direct alteration of erythrocyte membrane properties by 1-chloro-2,4-dinitrobenzene without oxidant challenge. Exp Hematol 21:114-8
Kuypers, F A; Lubin, B H; Yee, M et al. (1993) The distribution of erythrocyte phospholipids in hereditary spherocytosis demonstrates a minimal role for erythrocyte spectrin on phospholipid diffusion and asymmetry. Blood 81:1051-7
Zuo, L; Chen, E Y; Chang, C et al. (1992) A new mutation responsible for severe G6PD deficiency in two ethnic Chinese with different clinical presentations: determination by a direct PCR sequencing technique. Int J Hematol 55:39-44
Chiu, D T; Zuo, L; Chen, E et al. (1991) Two commonly occurring nucleotide base substitutions in Chinese G6PD variants. Biochem Biophys Res Commun 180:988-93
Chao, L T; Du, C S; Louie, E et al. (1991) A to G substitution identified in exon 2 of the G6PD gene among G6PD deficient Chinese. Nucleic Acids Res 19:6056
Chen, M J; Sorette, M P; Chiu, D T et al. (1991) Prehemolytic effects of hydrogen peroxide and t-butylhydroperoxide on selected red cell properties. Biochim Biophys Acta 1066:193-200
Scott, M D; Rouyer-Fessard, P; Lubin, B H et al. (1990) Entrapment of purified alpha-hemoglobin chains in normal erythrocytes. A model for beta thalassemia. J Biol Chem 265:17953-9

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