Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL039585-09
Application #
2219279
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1987-09-30
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wayne State University
Department
Type
Organized Research Units
DUNS #
City
Detroit
State
MI
Country
United States
Zip Code
48202
Darville, M I; Ho, Y S; Eizirik, D L (2000) NF-kappaB is required for cytokine-induced manganese superoxide dismutase expression in insulin-producing cells. Endocrinology 141:153-62
Ho, Y S; Vincent, R; Dey, M S et al. (1998) Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia. Am J Respir Cell Mol Biol 18:538-47
Ho, Y S; Dey, M S; Crapo, J D (1996) Antioxidant enzyme expression in rat lungs during hyperoxia. Am J Physiol 270:L810-8
Jackson, R M; Parish, G; Ho, Y S (1996) Effects of hypoxia on expression of superoxide dismutases in cultured ATII cells and lung fibroblasts. Am J Physiol 271:L955-62
Russell, W J; Ho, Y S; Parish, G et al. (1995) Effects of hypoxia on MnSOD expression in mouse lung. Am J Physiol 269:L221-6
Ho, Y S (1994) Transgenic models for the study of lung biology and disease. Am J Physiol 266:L319-53
Oberley, T D; Coursin, D B; Cihla, H P et al. (1993) Immunolocalization of manganese superoxide dismutase in normal and transgenic mice expressing the human enzyme. Histochem J 25:267-79
Subramanian, R; Volovsek, A; Ho, Y S (1993) Lack of change in MnSOD during ischemia/reperfusion of isolated rat heart. J Mol Cell Cardiol 25:1179-86
Ho, Y S; Howard, A J (1992) Cloning and characterization of the rat glutathione peroxidase gene. FEBS Lett 301:5-9
Ho, Y S; Howard, A J; Crapo, J D (1991) Molecular structure of a functional rat gene for manganese-containing superoxide dismutase. Am J Respir Cell Mol Biol 4:278-86

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