Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL039653-01A1S1
Application #
3356446
Study Section
Metabolism Study Section (MET)
Project Start
1988-09-30
Project End
1991-06-30
Budget Start
1988-09-30
Budget End
1989-06-30
Support Year
1
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Michael Reese Hosp & Medical Center (Chicago)
Department
Type
DUNS #
City
Chicago
State
IL
Country
United States
Zip Code
60616
Mazzone, Theodore (2010) Intensive glucose lowering and cardiovascular disease prevention in diabetes: reconciling the recent clinical trial data. Circulation 122:2201-11
Mazzone, Theodore; Chait, Alan; Plutzky, Jorge (2008) Cardiovascular disease risk in type 2 diabetes mellitus: insights from mechanistic studies. Lancet 371:1800-9
Lucic, Danijela; Huang, Zhi Hua; Gu, DeSheng et al. (2007) Cellular sphingolipids regulate macrophage apolipoprotein E secretion. Biochemistry 46:11196-204
Lucic, Danijela; Huang, Zhi Hua; Gu, De Sheng et al. (2007) Regulation of macrophage apoE secretion and sterol efflux by the LDL receptor. J Lipid Res 48:366-72
Fantuzzi, Giamila; Mazzone, Theodore (2007) Adipose tissue and atherosclerosis: exploring the connection. Arterioscler Thromb Vasc Biol 27:996-1003
Huang, Zhi H; Fitzgerald, Michael L; Mazzone, Theodore (2006) Distinct cellular loci for the ABCA1-dependent and ABCA1-independent lipid efflux mediated by endogenous apolipoprotein E expression. Arterioscler Thromb Vasc Biol 26:157-62
Huang, Zhi Hua; Gu, DeSheng; Mazzone, Theodore (2004) Oleic acid modulates the post-translational glycosylation of macrophage ApoE to increase its secretion. J Biol Chem 279:29195-201
Yue, Lili; Rasouli, Neda; Ranganathan, Gouri et al. (2004) Divergent effects of peroxisome proliferator-activated receptor gamma agonists and tumor necrosis factor alpha on adipocyte ApoE expression. J Biol Chem 279:47626-32
Huang, Z Hua; Gu, DeSheng; Lange, Yvonne et al. (2003) Expression of scavenger receptor BI facilitates sterol movement between the plasma membrane and the endoplasmic reticulum in macrophages. Biochemistry 42:3949-55
Huang, Zhi Hua; Mazzone, Theodore (2002) ApoE-dependent sterol efflux from macrophages is modulated by scavenger receptor class B type I expression. J Lipid Res 43:375-82

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