Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL039762-06A1
Application #
2219363
Study Section
Mammalian Genetics Study Section (MGN)
Project Start
1989-07-01
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Feng, Jinong; Drost, Joni B; Scaringe, William A et al. (2002) Mutations in the factor IX gene (F9) during the past 150 years have relative rates similar to ancient mutations. Hum Mutat 19:49-57
Hill, Kathleen A; Sommer, Steve S (2002) p53 as a mutagen test in breast cancer. Environ Mol Mutagen 39:216-27
Sommer, S S; Scaringe, W A; Hill, K A (2001) Human germline mutation in the factor IX gene. Mutat Res 487:1-17
Li, X; Scaringe, W A; Hill, K A et al. (2001) Frequency of recent retrotransposition events in the human factor IX gene. Hum Mutat 17:511-9
Li, X; Drost, J B; Roberts, S et al. (2000) Factor IX mutations in South Africans and African Americans are compatible with primarily endogenous influences upon recent germline mutations. Hum Mutat 16:371
Liu, J Z; Li, X; Drost, J et al. (2000) The human factor IX gene as germline mutagen test: samples from Mainland China have the putatively endogenous pattern of mutation. Hum Mutat 16:31-6
Drost, J B; Scaringe, W A; Jaloma-Cruz, A R et al. (2000) Novel hotspot detector software reveals a non-CpG hotspot of germline mutation in the factor IX gene (F9) in Latin Americans. Hum Mutat 16:203-10
Heit, J A; Ketterling, R P; Zapata, R E et al. (1999) Haemophilia B Brandenberg-type promoter mutation. Haemophilia 5:73-5
Thorland, E C; Drost, J B; Lusher, J M et al. (1999) Anaphylactic response to factor IX replacement therapy in haemophilia B patients: complete gene deletions confer the highest risk. Haemophilia 5:101-5
Ketterling, R P; Vielhaber, E; Li, X et al. (1999) Germline origins in the human F9 gene: frequent G:C-->A:T mosaicism and increased mutations with advanced maternal age. Hum Genet 105:629-40

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