Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL039827-10
Application #
2219385
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1988-03-01
Project End
1997-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Lilly, C M; Chapman, R W; Sehring, S J et al. (1996) Effects of interleukin 5-induced pulmonary eosinophilia on airway reactivity in the guinea pig. Am J Physiol 270:L368-75
Lilly, C M; Hall, A E; Rodger, I W et al. (1995) Substance P-induced histamine release in tracheally perfused guinea pig lungs. J Appl Physiol 78:1234-41
Lilly, C M; Bai, T R; Shore, S A et al. (1995) Neuropeptide content of lungs from asthmatic and nonasthmatic patients. Am J Respir Crit Care Med 151:548-53
Shore, S A; Martins, M A; Drazen, J M (1993) Pulmonary mechanical responses to intravenously administered capsaicin in guinea-pigs: effect of peptidase inhibitors. Pulm Pharmacol 6:193-9
Shore, S A; Sharpless, C; Drazen, J M (1993) Bronchoconstrictor activities of NP gamma and NPK in anaesthetized guinea-pigs: effect on NEP inhibition. Pulm Pharmacol 6:143-7
Lilly, C M; Martins, M A; Drazen, J M (1993) Peptidase modulation of vasoactive intestinal peptide pulmonary relaxation in tracheal superfused guinea pig lungs. J Clin Invest 91:235-43
Lilly, C M; Drazen, J M; Shore, S A (1993) Peptidase modulation of airway effects of neuropeptides. Proc Soc Exp Biol Med 203:388-404
Shore, S A; Martins, M A; Drazen, J M (1992) Effect of the NEP inhibitor SCH32615 on airway responses to intravenous substance P in guinea pigs. J Appl Physiol 73:1847-53
Shore, S A; Drazen, J M (1991) Relative bronchoconstrictor activity of neurokinin A and neurokinin A fragments in guinea pigs. J Appl Physiol 71:452-7
Martins, M A; Shore, S A; Drazen, J M (1991) Release of tachykinins by histamine, methacholine, PAF, LTD4, and substance P from guinea pig lungs. Am J Physiol 261:L449-55

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