Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL039924-10
Application #
2219445
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1987-09-30
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1998-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Xia, Y; Haddad, G G (2001) Major difference in the expression of delta- and mu-opioid receptors between turtle and rat brain. J Comp Neurol 436:202-10
Zhang, J; Haddad, G G; Xia, Y (2000) delta-, but not mu- and kappa-, opioid receptor activation protects neocortical neurons from glutamate-induced excitotoxic injury. Brain Res 885:143-53
Xia, Y; Fung, M L; O'Reilly, J P et al. (2000) Increased neuronal excitability after long-term O(2) deprivation is mediated mainly by sodium channels. Brain Res Mol Brain Res 76:211-9
Xia, Y; Haddad, G G (1999) Effect of prolonged O2 deprivation on Na+ channels: differential regulation in adult versus fetal rat brain. Neuroscience 94:1231-43
Friedman, J E; Chow, E J; Haddad, G G (1998) State of actin filaments is changed by anoxia in cultured rat neocortical neurons. Neuroscience 82:421-7
Croning, M D; Haddad, G G (1998) Comparison of brain slice chamber designs for investigations of oxygen deprivation in vitro. J Neurosci Methods 81:103-11
Xia, Y; Warshaw, J B; Haddad, G G (1997) Effect of chronic hypoxia on glucose transporters in heart and skeletal muscle of immature and adult rats. Am J Physiol 273:R1734-41
O'Reilly, J P; Haddad, G G (1996) Chronic hypoxia in vivo renders neocortical neurons more vulnerable to subsequent acute hypoxic stress. Brain Res 711:203-10
Marks, J D; Friedman, J E; Haddad, G G (1996) Vulnerability of CA1 neurons to glutamate is developmentally regulated. Brain Res Dev Brain Res 97:194-206
Xia, Y; Warshaw, J B; Haddad, G G (1995) Chronic hypoxia causes opposite effects on glucose transporter 1 mRNA in mature versus immature rat brain. Brain Res 675:224-30

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