Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL040411-03S1
Application #
3357590
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1988-04-01
Project End
1992-03-31
Budget Start
1990-04-01
Budget End
1991-03-31
Support Year
3
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Upchurch, G R; Valeri, C R; Khuri, S F et al. (1996) Effect of heparin on fibrinolytic activity and platelet function in vivo. Am J Physiol 271:H528-34
Grevelink, S A; Osborne, J; Loscalzo, J et al. (1995) Vasorelaxant and second messenger effects of maxadilan. J Pharmacol Exp Ther 272:33-7
Freedman, J E; Fabian, A; Loscalzo, J (1995) Impaired EDRF production by endothelial cells exposed to fibrin monomer and FDP. Am J Physiol 268:C520-6
Simon, D I; Ezratty, A M; Loscalzo, J (1994) The fibrin(ogen)olytic properties of cathepsin D. Biochemistry 33:6555-63
Gaston, B; Drazen, J M; Loscalzo, J et al. (1994) The biology of nitrogen oxides in the airways. Am J Respir Crit Care Med 149:538-51
Rabbani, L E; Loscalzo, J (1994) Recent observations on the role of hemostatic determinants in the development of the atherothrombotic plaque. Atherosclerosis 105:1-7
Slivka, A; Chuttani, R; Carr-Locke, D L et al. (1994) Inhibition of sphincter of Oddi function by the nitric oxide carrier S-nitroso-N-acetylcysteine in rabbits and humans. J Clin Invest 94:1792-8
Ouimet, H; Freedman, J E; Loscalzo, J (1994) Kinetics and mechanism of platelet-surface plasminogen activation by tissue-type plasminogen activator. Biochemistry 33:2970-6
Pasche, B; Ouimet, H; Francis, S et al. (1994) Structural changes in platelet glycoprotein IIb/IIIa by plasmin: determinants and functional consequences. Blood 83:404-14
Gaston, B; Drazen, J M; Jansen, A et al. (1994) Relaxation of human bronchial smooth muscle by S-nitrosothiols in vitro. J Pharmacol Exp Ther 268:978-84

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