Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL040506-07
Application #
2219629
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1988-04-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
7
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Washington University
Department
Pathology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130

  Publications

Dickeson, S K; Mathis, N L; Rahman, M et al. (1999) Determinants of ligand binding specificity of the alpha(1)beta(1) and alpha(2)beta(1) integrins. J Biol Chem 274:32182-91
Zutter, M M; Santoro, S A; Wu, J E et al. (1999) Collagen receptor control of epithelial morphogenesis and cell cycle progression. Am J Pathol 155:927-40
Bhattacharyya-Pakrasi, M; Dickeson, S K; Santoro, S A (1998) Alpha2beta1 integrin recognition of the carboxyl-terminal propeptide of type I procollagen: integrin recognition and feed-back regulation of matrix biosynthesis are mediated by distinct sequences. Matrix Biol 17:223-32
Dickeson, S K; Bhattacharyya-Pakrasi, M; Mathis, N L et al. (1998) Ligand binding results in divalent cation displacement from the alpha 2 beta 1 integrin I domain: evidence from terbium luminescence spectroscopy. Biochemistry 37:11280-8
Staatz, W D; Walsh, J J; Santoro, S A (1997) The alpha 2 beta 1 integrin binds to the CB4 peptide of the alpha 2(I) collagen chain. Biochem Mol Biol Int 42:577-82
Dickeson, S K; Walsh, J J; Santoro, S A (1997) Contributions of the I and EF hand domains to the divalent cation-dependent collagen binding activity of the alpha2beta1 integrin. J Biol Chem 272:7661-8
Wu, J E; Santoro, S A (1996) Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn 206:169-81
Zutter, M M; Fong, A M; Krigman, H R et al. (1992) Differential regulation of the alpha 2 beta 1 and alpha IIb beta 3 integrin genes during megakaryocytic differentiation of pluripotential K562 cells. J Biol Chem 267:20233-8
Burger, S R; Zutter, M M; Sturgill-Koszycki, S et al. (1992) Induced cell surface expression of functional alpha 2 beta 1 integrin during megakaryocytic differentiation of K562 leukemic cells. Exp Cell Res 202:28-35
Staatz, W D; Fok, K F; Zutter, M M et al. (1991) Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen. J Biol Chem 266:7363-7

Showing the most recent 10 out of 23 publications