Amiodarone Pulmonary Toxicity - Phosphoinositides &CA++

Wilson, Barbara D.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL040944-06
• Application #: 2219810
• Study Section: Toxicology Subcommittee 2 (TOX)
• Project Start: 1989-04-01
• Project End: 1997-11-30
• Budget Start: 1995-12-01
• Budget End: 1997-11-30
• Support Year: 6
• Fiscal Year: 1996

Institution

• Name: Albert Einstein Medical Center
• City: Philadelphia
• State: PA
• Country: United States
• Zip Code: 19141

Publications

Wilson, B D; Clarkson, C E; Lippmann, M L (1993) Amiodarone causes decreased cell-mediated immune responses and inhibits the phospholipase C signaling pathway. Lung 171:137-48

Wilson, B D; Clarkson, C E; Lippmann, M L (1991) Amiodarone-induced pulmonary inflammation. Correlation with drug dose and lung levels of drug, metabolite, and phospholipid. Am Rev Respir Dis 143:1110-4

Wilson, B D; Lippmann, M L (1990) Pulmonary accumulation of amiodarone and N-desethylamiodarone. Relationship to the development of pulmonary toxicity. Am Rev Respir Dis 141:1553-8