The cost and limited availability of blood products and the small but finite risks associated with their administration demands that physicians use this vital resource prudently. Yet, little formal attention is given to appropriate blood utilization strategies during either medical school or post-graduate training. Consequently, transfusion strategies may be idiosyncratic, inconsistent and not well-grounded in scientific evidence. The underlying goal of this research is to improve transfusion practice by the application of knowledge-based techniques (ie, expert systems) to support the independent Teaming and decision making of physicians while actively engaged in clinical practice. The first specific aim is to implement a knowledge-based system for the evaluation of requests for platelet transfusion. An existing expert system that reflects current scientific knowledge as well as the clinical heuristics necessary for appropriate practice will be expanded and enhanced.
The second aim i s to develop a physician's workstation incorporating the expert system so as to provide a prompt and reasoned critique of platelet transfusion plans at the time the physician formulates a plan. The effects of the workstation on physician learning and transfusion practice will be evaluated in a randomized controlled clinical trial using a two period crossover design. Physicians on the bone marrow transplant, adult oncology, and pediatric hematology/oncology services in a university hospital will be studied. The project 9 will demonstrate a novel and generalizable approach to improving the education and practice of physicians using platelet transfusions in a way that realistically deals with the complexity, variability and scope of clinical problems. Experience gained here will apply directly to enhancing knowledge and appropriate use of other blood products, laboratory tests, and many other health care resources.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL041086-02
Application #
3358560
Study Section
Special Emphasis Panel (SRC (PY))
Project Start
1990-07-01
Project End
1993-06-30
Budget Start
1991-07-01
Budget End
1992-06-30
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Turley, J P; Connelly, D P (1993) The relationship between nursing and medical cultures: implications for the design and implementation of a clinicians' workstation. Proc Annu Symp Comput Appl Med Care :233-7
Werth, G R; Connelly, D P (1992) Continuous quality improvement and medical informatics: the convergent synergy. Proc Annu Symp Comput Appl Med Care :631-5
Sielaff, B H; Scott, E P; Connelly, D P (1991) Design and preliminary evaluation of an expert system for platelet request evaluation. Transfusion 31:600-6