Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL041990-02
Application #
3359917
Study Section
Pathology A Study Section (PTHA)
Project Start
1988-12-01
Project End
1991-11-30
Budget Start
1989-12-01
Budget End
1990-11-30
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Zhao, Bin; Li, Yifu; Buono, Chiara et al. (2006) Constitutive receptor-independent low density lipoprotein uptake and cholesterol accumulation by macrophages differentiated from human monocytes with macrophage-colony-stimulating factor (M-CSF). J Biol Chem 281:15757-62
Kruth, Howard S; Jones, Nancy L; Huang, Wei et al. (2005) Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein. J Biol Chem 280:2352-60
Jones, N L; Saunders, J A; Mallory, R R (2000) Intracellular trafficking of pigeon beta-very low density lipoprotein and low density lipoprotein at low and high concentrations in pigeon macrophages. J Lipid Res 41:1823-31
Jones, N L; Reagan, J W; Willingham, M C (2000) The pathogenesis of foam cell formation: modified LDL stimulates uptake of co-incubated LDL via macropinocytosis. Arterioscler Thromb Vasc Biol 20:773-81
Jones, N L; Willingham, M C (1999) Modified LDLs are internalized by macrophages in part via macropinocytosis. Anat Rec 255:57-68
Jones, N L; Allen, N S; Willingham, M C et al. (1999) Modified LDLs induce and bind to membrane ruffles on macrophages. Anat Rec 255:44-56
Jones, N L (1997) Simultaneous labeling of lipoprotein intracellular trafficking in pigeon monocyte-derived macrophages. Am J Pathol 150:1113-24
Zha, X; Tabas, I; Leopold, P L et al. (1997) Evidence for prolonged cell-surface contact of acetyl-LDL before entry into macrophages. Arterioscler Thromb Vasc Biol 17:1421-31
Lewis, J C; Jones, N L; Hermanns, M I et al. (1995) Tissue factor expression during coculture of endothelial cells and monocytes. Exp Mol Pathol 62:207-18
Jones, N L; Gupta, M; Lewis, J C (1995) The LDL receptor and LRP are receptors for beta VLDL on pigeon monocyte-derived macrophages. Virchows Arch 426:189-98

Showing the most recent 10 out of 15 publications