Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL042119-08
Application #
2220296
Study Section
Pathology A Study Section (PTHA)
Project Start
1988-12-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
8
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Pathology
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
Rekhter, M D; Simari, R D; Work, C W et al. (1998) Gene transfer into normal and atherosclerotic human blood vessels. Circ Res 82:1243-52
Stephan, D; San, H; Yang, Z Y et al. (1997) Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon. Mol Med 3:593-9
Rekhter, M D; O'Brien, E; Shah, N et al. (1996) The importance of thrombus organization and stellate cell phenotype in collagen I gene expression in human, coronary atherosclerotic and restenotic lesions. Cardiovasc Res 32:496-502
Isik, F F; Coughlin, S R; Nelken, N A et al. (1996) JE gene expression in an animal model of acute arterial graft rejection. J Surg Res 60:224-31
Simari, R D; San, H; Rekhter, M et al. (1996) Regulation of cellular proliferation and intimal formation following balloon injury in atherosclerotic rabbit arteries. J Clin Invest 98:225-35
Thackray, B D; Burns, D H; Ferguson, M S et al. (1995) A new method for studying plaque morphology. Am J Card Imaging 9:149-56
Pompili, V J; Gordon, D; San, H et al. (1995) Expression and function of a recombinant PDGF B gene in porcine arteries. Arterioscler Thromb Vasc Biol 15:2254-64
Kolpakov, V; Gordon, D; Kulik, T J (1995) Nitric oxide-generating compounds inhibit total protein and collagen synthesis in cultured vascular smooth muscle cells. Circ Res 76:305-9
Rekhter, M D; Gordon, D (1995) Active proliferation of different cell types, including lymphocytes, in human atherosclerotic plaques. Am J Pathol 147:668-77
Hatsukami, T S; Thackray, B D; Primozich, J F et al. (1994) Echolucent regions in carotid plaque: preliminary analysis comparing three-dimensional histologic reconstructions to sonographic findings. Ultrasound Med Biol 20:743-9

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