ALPHA-1 Adrenergic Regulation of Cardiac Gene Expression

Simpson, Paul C.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL042150-07
• Application #: 2220320
• Study Section: Cardiovascular and Pulmonary Research A Study Section (CVA)
• Project Start: 1989-07-01
• Project End: 1997-06-30
• Budget Start: 1996-07-22
• Budget End: 1997-06-30
• Support Year: 7
• Fiscal Year: 1996

Institution

• Name: University of California San Francisco
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 073133571
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Yang, Jingyue; Han, Xianlin; Gross, Richard W (2003) Identification of hepatic peroxisomal phospholipase A(2) and characterization of arachidonic acid-containing choline glycerophospholipids in hepatic peroxisomes. FEBS Lett 546:247-50

Nakamura, A; Rokosh, D G; Paccanaro, M et al. (2001) LV systolic performance improves with development of hypertrophy after transverse aortic constriction in mice. Am J Physiol Heart Circ Physiol 281:H1104-12

Yue, P; Massie, B M; Simpson, P C et al. (1998) Cytokine expression increases in nonmyocytes from rats with postinfarction heart failure. Am J Physiol 275:H250-8

Yue, P; Long, C S; Austin, R et al. (1998) Post-infarction heart failure in the rat is associated with distinct alterations in cardiac myocyte molecular phenotype. J Mol Cell Cardiol 30:1615-30

Kariya, K; Karns, L R; Simpson, P C (1991) Expression of a constitutively activated mutant of the beta-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene. J Biol Chem 266:10023-6

Waspe, L E; Ordahl, C P; Simpson, P C (1990) The cardiac beta-myosin heavy chain isogene is induced selectively in alpha 1-adrenergic receptor-stimulated hypertrophy of cultured rat heart myocytes. J Clin Invest 85:1206-14