Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL042507-09
Application #
2691907
Study Section
Project Start
1997-07-01
Project End
1998-08-30
Budget Start
Budget End
Support Year
9
Fiscal Year
1998
Total Cost
Indirect Cost
Imuta, Naohiko; Hori, Osamu; Kitao, Yasuko et al. (2007) Hypoxia-mediated induction of heme oxygenase type I and carbon monoxide release from astrocytes protects nearby cerebral neurons from hypoxia-mediated apoptosis. Antioxid Redox Signal 9:543-52
Biancone, L; Cantaluppi, V; Segoloni, G et al. (2000) Role of platelet-activating factor in functional alterations induced by xenoreactive antibodies in porcine endothelial cells. Transplantation 70:1198-205
Yan, S F; Lu, J; Zou, Y S et al. (2000) Protein kinase C-beta and oxygen deprivation. A novel Egr-1-dependent pathway for fibrin deposition in hypoxemic vasculature. J Biol Chem 275:11921-8
Maruyama, S; Cantu 3rd, E; Galili, U et al. (2000) alpha-galactosyl epitopes on glycoproteins of porcine renal extracellular matrix. Kidney Int 57:655-63
Maruyama, S; Cantu 3rd, E; DeMartino, C et al. (1999) Interaction of baboon anti-alpha-galactosyl antibody with pig tissues. Am J Pathol 155:1635-49
Yan, S F; Lu, J; Zou, Y S et al. (1999) Hypoxia-associated induction of early growth response-1 gene expression. J Biol Chem 274:15030-40
Maruyama, S; Cantu 3rd, E; Demartino, C et al. (1999) Membranous glomerulonephritis induced in the pig by antibody to angiotensin-converting enzyme: considerations on its relevance to the pathogenesis of human idiopathic membranous glomerulonephritis. J Am Soc Nephrol 10:2102-8
Maruyama, S; Cantu E3rd; Pernis, B et al. (1999) Alpha-galactosyl antibody redistributes alpha-galactosyl at the surface of pig blood and endothelial cells. Transpl Immunol 7:101-6
Niitsu, Y; Hori, O; Yamaguchi, A et al. (1999) Exposure of cultured primary rat astrocytes to hypoxia results in intracellular glucose depletion and induction of glycolytic enzymes. Brain Res Mol Brain Res 74:26-34
Yan, S F; Zou, Y S; Gao, Y et al. (1998) Tissue factor transcription driven by Egr-1 is a critical mechanism of murine pulmonary fibrin deposition in hypoxia. Proc Natl Acad Sci U S A 95:8298-303

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