Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL042525-05
Application #
2220556
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1991-06-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Minnesota Twin Cities
Department
Pharmacology
Type
Schools of Medicine
DUNS #
168559177
City
Minneapolis
State
MN
Country
United States
Zip Code
55455
Trachte, George J (2003) Natriuretic peptides suppress protein kinase C activity to reduce evoked dopamine efflux from pheochromocytoma (PC12) cells. Endocrinology 144:94-100
Trachte, G J (2000) Depletion of natriuretic peptide C receptors eliminates inhibitory effects of C-type natriuretic peptide on evoked neurotransmitter efflux. J Pharmacol Exp Ther 294:210-5
Kanwal, S; Lowe, D G; Trachte, G J (1999) Intracellular fragments of the natriuretic peptide receptor-C (NPR-C) attenuate dopamine efflux. Endocrinology 140:1118-24
Kanwal, S; Elmquist, B J; Trachte, G J (1997) Atrial natriuretic peptide inhibits evoked catecholamine release by altering sensitivity to calcium. J Pharmacol Exp Ther 283:426-33
Trachte, G J; Kanwal, S; Elmquist, B J et al. (1995) C-type natriuretic peptide neuromodulates via ""clearance"" receptors. Am J Physiol 268:C978-84
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Trachte, G J (1993) Atrial natriuretic factor alters neurotransmission independently of guanylate cyclase-coupled receptors in the rabbit vas deferens. J Pharmacol Exp Ther 264:1227-33
Anand-Srivastava, M B; Trachte, G J (1993) Atrial natriuretic factor receptors and signal transduction mechanisms. Pharmacol Rev 45:455-97
Drewett, J G; Ziegler, R J; Trachte, G J (1992) Neuromodulatory effects of atrial natriuretic peptides correlate with an inhibition of adenylate cyclase but not an activation of guanylate cyclase. J Pharmacol Exp Ther 260:689-96