Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL042666-05
Application #
3361003
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1990-01-01
Project End
1994-12-31
Budget Start
1993-01-01
Budget End
1993-12-31
Support Year
5
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Boulom, V; Lee, H-W; Zhao, L et al. (2002) Stimulation of DNA synthesis, activation of mitogen-activated protein kinase ERK2 and nuclear accumulation of c-fos in human aortic smooth muscle cells by ketamine. Cell Prolif 35:155-65
Zhao, L; Eghbali-Webb, M (2001) Release of pro- and anti-angiogenic factors by human cardiac fibroblasts: effects on DNA synthesis and protection under hypoxia in human endothelial cells. Biochim Biophys Acta 1538:273-82
Griffin, M; Lee, H W; Zhao, L et al. (2000) Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen. Mol Cell Biochem 215:21-30
Lee, H W; Eghbali-Webb, M (1998) Estrogen enhances proliferative capacity of cardiac fibroblasts by estrogen receptor- and mitogen-activated protein kinase-dependent pathways. J Mol Cell Cardiol 30:1359-68
Agocha, A; Sigel, A V; Eghbali-Webb, M (1997) Characterization of adult human heart fibroblasts in culture: a comparative study of growth, proliferation and collagen production in human and rabbit cardiac fibroblasts and their response to transforming growth factor-beta1. Cell Tissue Res 288:87-93
Agocha, A; Lee, H W; Eghbali-Webb, M (1997) Hypoxia regulates basal and induced DNA synthesis and collagen type I production in human cardiac fibroblasts: effects of transforming growth factor-beta1, thyroid hormone, angiotensin II and basic fibroblast growth factor. J Mol Cell Cardiol 29:2233-44
Agocha, A E; Eghbali-Webb, M (1997) A simple method for preparation of cultured cardiac fibroblasts from adult human ventricular tissue. Mol Cell Biochem 172:195-8
Klein, L E; Sigel, A V; Douglas, J A et al. (1996) Upregulation of collagen type I gene expression in the ventricular myocardium of thyroidectomized male and female rats. J Mol Cell Cardiol 28:33-42
Sigel, A V; Centrella, M; Eghbali-Webb, M (1996) Regulation of proliferative response of cardiac fibroblasts by transforming growth factor-beta 1. J Mol Cell Cardiol 28:1921-9
Rosenkranz-Weiss, P; Tomek, R J; Mathew, J et al. (1994) Gender-specific differences in expression of mRNAs for functional and structural proteins in rat ventricular myocardium. J Mol Cell Cardiol 26:261-70

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