Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL042813-06
Application #
2220692
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1993-08-15
Project End
1997-06-30
Budget Start
1994-07-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Texas Health Center at Tyler
Department
Biochemistry
Type
Other Domestic Higher Education
DUNS #
City
Tyler
State
TX
Country
United States
Zip Code
75708
Rao, L V; Pendurthi, U R (1998) Tissue factor on cells. Blood Coagul Fibrinolysis 9 Suppl 1:S27-35
Idell, S; Pendurthi, U; Pueblitz, S et al. (1998) Tissue factor pathway inhibitor in tetracycline-induced pleuritis in rabbits. Thromb Haemost 79:649-55
Pendurthi, U R; Williams, J T; Rao, L V (1997) Inhibition of tissue factor gene activation in cultured endothelial cells by curcumin. Suppression of activation of transcription factors Egr-1, AP-1, and NF-kappa B. Arterioscler Thromb Vasc Biol 17:3406-13
Sorensen, B B; Persson, E; Freskgard, P O et al. (1997) Incorporation of an active site inhibitor in factor VIIa alters the affinity for tissue factor. J Biol Chem 272:11863-8
Pendurthi, U R; Williams, J T; Rao, L V (1997) Acidic and basic fibroblast growth factors suppress transcriptional activation of tissue factor and other inflammatory genes in endothelial cells. Arterioscler Thromb Vasc Biol 17:940-6
Rao, L V; Williams, T; Rapaport, S I (1996) Studies of the activation of factor VII bound to tissue factor. Blood 87:3738-48
Rao, L V; Hoang, A D; Rapaport, S I (1996) Mechanism and effects of the binding of lupus anticoagulant IgG and prothrombin to surface phospholipid. Blood 88:4173-82
Rao, L V; Rapaport, S I (1996) Cells and the activation of factor VII. Haemostasis 26 Suppl 1:1-5
Sevinsky, J R; Rao, L V; Ruf, W (1996) Ligand-induced protease receptor translocation into caveolae: a mechanism for regulating cell surface proteolysis of the tissue factor-dependent coagulation pathway. J Cell Biol 133:293-304
Zivelin, A; Rao, L V; Rapaport, S I (1995) Evidence for an essential role of tissue factor dependent blood coagulation in the pathogenesis of the local Shwartzman reaction. Blood Cells Mol Dis 21:9-19

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