Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL043757-04
Application #
2221159
Study Section
Pathology A Study Section (PTHA)
Project Start
1992-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
4
Fiscal Year
1995
Total Cost
Indirect Cost
Name
University of Michigan Ann Arbor
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
791277940
City
Ann Arbor
State
MI
Country
United States
Zip Code
48109
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Rekhter, M D; Simari, R D; Work, C W et al. (1998) Gene transfer into normal and atherosclerotic human blood vessels. Circ Res 82:1243-52
Stephan, D; San, H; Yang, Z Y et al. (1997) Inhibition of vascular smooth muscle cell proliferation and intimal hyperplasia by gene transfer of beta-interferon. Mol Med 3:593-9
Schott, E; Tostes, R C; San, H et al. (1997) Expression of a recombinant preproendothelin-1 gene in arteries stimulates vascular contractility. Am J Physiol 272:H2385-93
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Pompili, V J; Gordon, D; San, H et al. (1995) Expression and function of a recombinant PDGF B gene in porcine arteries. Arterioscler Thromb Vasc Biol 15:2254-64
Yang, Z Y; Perkins, N D; Ohno, T et al. (1995) The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nat Med 1:1052-6
Fishel, R S; Thourani, V; Eisenberg, S J et al. (1995) Fibroblast growth factor stimulates angiotensin converting enzyme expression in vascular smooth muscle cells. Possible mediator of the response to vascular injury. J Clin Invest 95:377-87
Muller, D W; Gordon, D; San, H et al. (1994) Catheter-mediated pulmonary vascular gene transfer and expression. Circ Res 75:1039-49
Nabel, E G; Yang, Z; Liptay, S et al. (1993) Recombinant platelet-derived growth factor B gene expression in porcine arteries induce intimal hyperplasia in vivo. J Clin Invest 91:1822-9

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