Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL044514-11
Application #
6608145
Study Section
Pharmacology A Study Section (PHRA)
Program Officer
Velletri, Paul A
Project Start
1991-01-15
Project End
2005-07-31
Budget Start
2003-08-01
Budget End
2004-07-31
Support Year
11
Fiscal Year
2003
Total Cost
$267,750
Indirect Cost
Name
Case Western Reserve University
Department
Nutrition
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Xu, Chuan; Arinze, Ifeanyi J; Johnson, Janean et al. (2008) Metabolic dysregulation in the SHROB rat reflects abnormal expression of transcription factors and enzymes that regulate carbohydrate metabolism. J Nutr Biochem 19:305-12
Ernsberger, Paul; Johnson, Janean L; Rosenthal, Talma et al. (2007) Therapeutic actions of allylmercaptocaptopril and captopril in a rat model of metabolic syndrome. Am J Hypertens 20:866-74
Ernsberger, Paul; Koletsky, Richard J (2007) Metabolic actions of angiotensin receptor antagonists: PPAR-gamma agonist actions or a class effect? Curr Opin Pharmacol 7:140-5
Ishizuka, T; Ernsberger, P; Liu, S et al. (1998) Phenotypic consequences of a nonsense mutation in the leptin receptor gene (fak) in obese spontaneously hypertensive Koletsky rats (SHROB). J Nutr 128:2299-306
Ernsberger, P; Friedman, J E; Koletsky, R J (1997) The I1-imidazoline receptor: from binding site to therapeutic target in cardiovascular disease. J Hypertens Suppl 15:S9-23