Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL044761-06
Application #
2221672
Study Section
Cardiovascular and Renal Study Section (CVB)
Project Start
1991-07-01
Project End
1996-10-31
Budget Start
1994-04-01
Budget End
1996-10-31
Support Year
6
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Physiology
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Brown, C; Lin, Y; Hassid, A (2001) Requirement of protein tyrosine phosphatase SHP2 for NO-stimulated vascular smooth muscle cell motility. Am J Physiol Heart Circ Physiol 281:H1598-605
Brown, C; Pan, X; Hassid, A (1999) Nitric oxide and C-type atrial natriuretic peptide stimulate primary aortic smooth muscle cell migration via a cGMP-dependent mechanism: relationship to microfilament dissociation and altered cell morphology. Circ Res 84:655-67
Hassid, A; Yao, J; Huang, S (1999) NO alters cell shape and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B activation. Am J Physiol 277:H1014-26
Hassid, A; Huang, S; Yao, J (1999) Role of PTP-1B in aortic smooth muscle cell motility and tyrosine phosphorylation of focal adhesion proteins. Am J Physiol 277:H192-8
Kaur, K; Yao, J; Pan, X et al. (1998) NO decreases phosphorylation of focal adhesion proteins via reduction of Ca in rat aortic smooth muscle cells. Am J Physiol 274:H1613-9
Dhaunsi, G S; Matthews, C; Kaur, K et al. (1997) NO increases protein tyrosine phosphatase activity in smooth muscle cells: relationship to antimitogenesis. Am J Physiol 272:H1342-9
Dhaunsi, G S; Hassid, A (1996) Atrial and C-type natriuretic peptides amplify growth factor activity in primary aortic smooth muscle cells. Cardiovasc Res 31:37-47
Cahill, P A; Hassid, A (1994) ANF-C-receptor-mediated inhibition of aortic smooth muscle cell proliferation and thymidine kinase activity. Am J Physiol 266:R194-203
Hassid, A; Arabshahi, H; Bourcier, T et al. (1994) Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells. Am J Physiol 267:H1040-8
Cahill, P A; Hassid, A (1993) Differential antimitogenic effectiveness of atrial natriuretic peptides in primary versus subcultured rat aortic smooth muscle cells: relationship to expression of ANF-C receptors. J Cell Physiol 154:28-38

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