Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL045048-06
Application #
2221872
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1990-07-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1997-11-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Medical College of Wisconsin
Department
Radiation-Diagnostic/Oncology
Type
Schools of Medicine
DUNS #
073134603
City
Milwaukee
State
WI
Country
United States
Zip Code
53226
Eells, J T; Henry, M M; Gross, G J et al. (2000) Increased mitochondrial K(ATP) channel activity during chronic myocardial hypoxia: is cardioprotection mediated by improved bioenergetics? Circ Res 87:915-21
Baker, J E; Holman, P; Kalyanaraman, B et al. (1998) Adaptation of hearts to chronic hypoxia increases tolerance to subsequent ischemia by increased nitric oxide production. Adv Exp Med Biol 454:203-17
Ferguson, E; Parthasarathy, S; Joseph, J et al. (1998) Generation and initial characterization of a novel polyclonal antibody directed against homocysteine thiolactone-modified low density lipoprotein. J Lipid Res 39:925-33
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Baker, J E; Curry, B D; Olinger, G N et al. (1997) Increased tolerance of the chronically hypoxic immature heart to ischemia. Contribution of the KATP channel. Circulation 95:1278-85
Baker, J E; Contney, S J; Gross, G J et al. (1997) KATP channel activation in a rabbit model of chronic myocardial hypoxia. J Mol Cell Cardiol 29:845-8
Hogg, N; Singh, R J; Kalyanaraman, B (1996) The role of glutathione in the transport and catabolism of nitric oxide. FEBS Lett 382:223-8
Kalyanaraman, B (1996) Detection of nitric oxide by electron spin resonance in chemical, photochemical, cellular, physiological, and pathophysiological systems. Methods Enzymol 268:168-87
Konorev, E A; Joseph, J; Kalyanaraman, B (1996) S-nitrosoglutathione induces formation of nitrosylmyoglobin in isolated hearts during cardioplegic ischemia--an electron spin resonance study. FEBS Lett 378:111-4

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