Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL045198-05
Application #
2221997
Study Section
Pharmacology A Study Section (PHRA)
Project Start
1990-07-01
Project End
1996-12-31
Budget Start
1994-07-01
Budget End
1996-12-31
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Anesthesiology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Dietrich, Alexander; Mederos Y Schnitzler, Michael; Gollasch, Maik et al. (2005) Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol Cell Biol 25:6980-9
Birnbaumer, L; Boulay, G; Brown, D et al. (2000) Mechanism of capacitative Ca2+ entry (CCE): interaction between IP3 receptor and TRP links the internal calcium storage compartment to plasma membrane CCE channels. Recent Prog Horm Res 55:127-61; discussion 161-2
Wang, W; O'Connell, B; Dykeman, R et al. (1999) Cloning of Trp1beta isoform from rat brain: immunodetection and localization of the endogenous Trp1 protein. Am J Physiol 276:C969-79
Vannier, B; Peyton, M; Boulay, G et al. (1999) Mouse trp2, the homologue of the human trpc2 pseudogene, encodes mTrp2, a store depletion-activated capacitative Ca2+ entry channel. Proc Natl Acad Sci U S A 96:2060-4
Hurst, R S; Zhu, X; Boulay, G et al. (1998) Ionic currents underlying HTRP3 mediated agonist-dependent Ca2+ influx in stably transfected HEK293 cells. FEBS Lett 422:333-8
Vannier, B; Zhu, X; Brown, D et al. (1998) The membrane topology of human transient receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry. J Biol Chem 273:8675-9
Zhu, X; Jiang, M; Birnbaumer, L (1998) Receptor-activated Ca2+ influx via human Trp3 stably expressed in human embryonic kidney (HEK)293 cells. Evidence for a non-capacitative Ca2+ entry. J Biol Chem 273:133-42
Jiang, M; Boulay, G; Spicher, K et al. (1997) Inactivation of the G alpha i2 and G alpha o genes by homologous recombination. Receptors Channels 5:187-92
Boulay, G; Zhu, X; Peyton, M et al. (1997) Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein. J Biol Chem 272:29672-80
Birnbaumer, L; Zhu, X; Jiang, M et al. (1996) On the molecular basis and regulation of cellular capacitative calcium entry: roles for Trp proteins. Proc Natl Acad Sci U S A 93:15195-202

Showing the most recent 10 out of 23 publications