Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL045243-03S1
Application #
3364212
Study Section
Diagnostic Radiology Study Section (RNM)
Project Start
1990-07-01
Project End
1994-06-30
Budget Start
1992-07-01
Budget End
1994-06-30
Support Year
3
Fiscal Year
1992
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Pratt, R G; Zheng, J; Stewart, B K et al. (1997) Application of a 3D volume 19F MR imaging protocol for mapping oxygen tension (pO2) in perfluorocarbons at low field. Magn Reson Med 37:307-13
Thomas, S R; Pratt, R G; Millard, R W et al. (1996) In vivo PO2 imaging in the porcine model with perfluorocarbon F-19 NMR at low field. Magn Reson Imaging 14:103-14
McGoron, A J; Pratt, R; Zhang, J et al. (1994) Perfluorocarbon distribution to liver, lung and spleen of emulsions of perfluorotributylamine (FTBA) in pigs and rats and perfluorooctyl bromide (PFOB) in rats and dogs by 19F NMR spectroscopy. Artif Cells Blood Substit Immobil Biotechnol 22:1243-50
Thomas, S R; Millard, R W; Pratt, R G et al. (1994) Quantitative pO2 imaging in vivo with perfluorocarbon F-19 NMR: tracking oxygen from the airway through the blood to organ tissues. Artif Cells Blood Substit Immobil Biotechnol 22:1029-42
Millard, R W; McGoron, A J (1994) Lung functions after intravenous or intraperitoneal administration of perfluorooctyl bromide (PFOB) or perfluorotributylamine (FTBA) emulsions. Artif Cells Blood Substit Immobil Biotechnol 22:1251-8
Thomas, S R; Pratt, R G; Millard, R W et al. (1994) Evaluation of the influence of the aqueous phase bioconstituent environment on the F-19 T1 of perfluorocarbon blood substitute emulsions. J Magn Reson Imaging 4:631-5
Samaratunga, R C; Pratt, R G; Zhu, Y et al. (1994) Implementation of a modified birdcage resonator for 19F/1H MRI at low fields (0.14 T). Med Phys 21:697-705
Millard, R W (1994) Oxygen solubility, rheology and hemodynamics of perfluorocarbon emulsion blood substitutes. Artif Cells Blood Substit Immobil Biotechnol 22:235-44
Pratt, R G; Thomas, S R; Millard, R W et al. (1992) Quantitation of perfluorocarbon blood substitutes in tissues using F-19 magnetic resonance spectroscopy. Biomater Artif Cells Immobilization Biotechnol 20:921-4