Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL045286-06
Application #
2222050
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1990-07-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
National Jewish Health
Department
Type
DUNS #
City
Denver
State
CO
Country
United States
Zip Code
80206
Ferguson, J Scott; Martin, Jennifer L; Azad, Abul K et al. (2006) Surfactant protein D increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages. Infect Immun 74:7005-9
Piboonpocanun, Surapon; Chiba, Hirofumi; Mitsuzawa, Hiroaki et al. (2005) Surfactant protein A binds Mycoplasma pneumoniae with high affinity and attenuates its growth by recognition of disaturated phosphatidylglycerols. J Biol Chem 280:9-17
Allen, Martin J; Laederach, Alain; Reilly, Peter J et al. (2004) Arg343 in human surfactant protein D governs discrimination between glucose and N-acetylglucosamine ligands. Glycobiology 14:693-700
Chmura, Kathryn; Lutz, Ryan D; Chiba, Hirofumi et al. (2003) Mycoplasma pneumoniae antigens stimulate interleukin-8. Chest 123:425S
Beharka, Alison A; Gaynor, Cecilia D; Kang, Byoung K et al. (2002) Pulmonary surfactant protein A up-regulates activity of the mannose receptor, a pattern recognition receptor expressed on human macrophages. J Immunol 169:3565-73
Ferguson, J Scott; Voelker, Dennis R; Ufnar, Jennifer A et al. (2002) Surfactant protein D inhibition of human macrophage uptake of Mycobacterium tuberculosis is independent of bacterial agglutination. J Immunol 168:1309-14
Chiba, Hirofumi; Pattanajitvilai, Surapon; Evans, Amanda J et al. (2002) Human surfactant protein D (SP-D) binds Mycoplasma pneumoniae by high affinity interactions with lipids. J Biol Chem 277:20379-85
Allen, M J; Voelker, D R; Mason, R J (2001) Interactions of surfactant proteins A and D with Saccharomyces cerevisiae and Aspergillus fumigatus. Infect Immun 69:2037-44
Osanai, K; Mason, R J; Voelker, D R (2001) Pulmonary surfactant phosphatidylcholine transport bypasses the brefeldin A sensitive compartment of alveolar type II cells. Biochim Biophys Acta 1531:222-9
Sano, H; Chiba, H; Iwaki, D et al. (2000) Surfactant proteins A and D bind CD14 by different mechanisms. J Biol Chem 275:22442-51

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