Molecular Mechanisms of Apolipoprotein B Biogenesis

Lingappa, Vishwanath R.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL045480-05
• Application #: 2222176
• Study Section: Metabolism Study Section (MET)
• Project Start: 1991-01-01
• Project End: 1996-12-31
• Budget Start: 1995-01-01
• Budget End: 1996-12-31
• Support Year: 5
• Fiscal Year: 1995

Institution

• Name: University of California San Francisco
• Department: Physiology
• Type: Schools of Medicine
• DUNS #: 073133571
• City: San Francisco
• State: CA
• Country: United States
• Zip Code: 94143

Publications

Hegde, R S; Voigt, S; Rapoport, T A et al. (1998) TRAM regulates the exposure of nascent secretory proteins to the cytosol during translocation into the endoplasmic reticulum. Cell 92:621-31

Kivlen, M H; Dorsey, C A; Lingappa, V R et al. (1997) Asymmetric distribution of pause transfer sequences in apolipoprotein B-100. J Lipid Res 38:1149-62

Hegde, R S; Lingappa, V R (1996) Sequence-specific alteration of the ribosome-membrane junction exposes nascent secretory proteins to the cytosol. Cell 85:217-28

Chuck, S L; Lingappa, V R (1993) Analysis of a pause transfer sequence from apolipoprotein B. J Biol Chem 268:22794-801

Chuck, S L; Lingappa, V R (1992) Pause transfer: a topogenic sequence in apolipoprotein B mediates stopping and restarting of translocation. Cell 68:9-21