Regulation of Myosin Heavy Chain Alpha Gene by Camp

Zak, Radovan

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL045646-06
• Application #: 2222337
• Study Section: Cardiovascular and Renal Study Section (CVB)
• Project Start: 1991-08-26
• Project End: 1999-07-31
• Budget Start: 1996-08-01
• Budget End: 1997-07-31
• Support Year: 6
• Fiscal Year: 1996

Institution

• Name: University of Chicago
• Department: Internal Medicine/Medicine
• Type: Schools of Medicine
• DUNS #: 225410919
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60637

Publications

Gupta, M P; Kogut, P; Gupta, M (2000) Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability. Nucleic Acids Res 28:3168-77

Gupta, M; Zak, R; Libermann, T A et al. (1998) Tissue-restricted expression of the cardiac alpha-myosin heavy chain gene is controlled by a downstream repressor element containing a palindrome of two ets-binding sites. Mol Cell Biol 18:7243-58

Wiesner, R J; Ehmke, H; Faulhaber, J et al. (1997) Dissociation of left ventricular hypertrophy, beta-myosin heavy chain gene expression, and myosin isoform switch in rats after ascending aortic stenosis. Circulation 95:1253-9

Gupta, M P; Gupta, M; Jakovcic, S et al. (1996) Catecholamines and cardiac growth. Mol Cell Biochem 163-164:203-10

Gupta, M P; Gupta, M; Zak, R (1994) An E-box/M-CAT hybrid motif and cognate binding protein(s) regulate the basal muscle-specific and cAMP-inducible expression of the rat cardiac alpha-myosin heavy chain gene. J Biol Chem 269:29677-87

Wiesner, R J; Kurowski, T T; Zak, R (1992) Regulation by thyroid hormone of nuclear and mitochondrial genes encoding subunits of cytochrome-c oxidase in rat liver and skeletal muscle. Mol Endocrinol 6:1458-67