The applicants hypothesize that the lesions of aortic and coronary atherosclerosis begin in childhood; that they progress during young adulthood to form the raised lesions responsible for clinically manifest atherosclerotic disease in middle age; that progression is associated with the risk factors for adult atherosclerotic disease; and that the pathogenesis of, and the risk factors associated with, atherosclerosis are similar in whites and blacks, males and females.

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL045720-07
Application #
2445213
Study Section
Special Emphasis Panel (ZHL1-CCT-H (F3))
Project Start
1991-04-01
Project End
1998-12-31
Budget Start
1997-07-01
Budget End
1998-12-31
Support Year
7
Fiscal Year
1997
Total Cost
Indirect Cost
Name
Louisiana State University Hsc New Orleans
Department
Pathology
Type
Schools of Dentistry
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
Bosworth, H B; Siegler, I C; Olsen, M K et al. (2000) Social support and quality of life in patients with coronary artery disease. Qual Life Res 9:829-39
Bosworth, H B; Siegler, I C; Brummett, B H et al. (1999) The association between self-rated health and mortality in a well-characterized sample of coronary artery disease patients. Med Care 37:1226-36
Bosworth, H B; Siegler, I C; Brummett, B H et al. (1999) The relationship between self-rated health and health status among coronary artery patients. J Aging Health 11:565-84