Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL046668-01
Application #
3365780
Study Section
Special Emphasis Panel (SRC (JI))
Project Start
1991-03-10
Project End
1994-12-31
Budget Start
1991-03-10
Budget End
1991-12-31
Support Year
1
Fiscal Year
1991
Total Cost
Indirect Cost
Name
Beth Israel Deaconess Medical Center
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02215
Sato, T; Fuse, A; Niimi, H et al. (1998) Binding and regulation of thrombopoietin to human megakaryocytes. Br J Haematol 100:704-11
Raja, S; Avraham, S; Avraham, H (1997) Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism. J Biol Chem 272:10941-7
Banu, N; Price, D J; London, R et al. (1996) Modulation of megakaryocytopoiesis by human macrophage-stimulating protein, the ligand for the RON receptor. J Immunol 156:2933-40
Li, J; Avraham, H; Rogers, R A et al. (1996) Characterization of RAFTK, a novel focal adhesion kinase, and its integrin-dependent phosphorylation and activation in megakaryocytes. Blood 88:417-28
Ellis, M H; Avraham, H; Groopman, J E (1995) The regulation of megakaryocytopoiesis. Blood Rev 9:1-6
Avraham, H; Ellis, M H; Jhun, B H et al. (1995) Tyrosine kinases in megakaryocytopoiesis. Stem Cells 13:380-92
Jhun, B H; Rivnay, B; Price, D et al. (1995) The MATK tyrosine kinase interacts in a specific and SH2-dependent manner with c-Kit. J Biol Chem 270:9661-6
Richardson, P M; Zon, L I (1995) Molecular cloning of a cDNA with a novel domain present in the tre-2 oncogene and the yeast cell cycle regulators BUB2 and cdc16. Oncogene 11:1139-48
Avraham, S; London, R; Fu, Y et al. (1995) Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain. J Biol Chem 270:27742-51
Avraham, S; Jiang, S; Ota, S et al. (1995) Structural and functional studies of the intracellular tyrosine kinase MATK gene and its translated product. J Biol Chem 270:1833-42

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