Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047250-08
Application #
2874043
Study Section
Project Start
1996-08-01
Project End
1999-07-31
Budget Start
1998-08-01
Budget End
1999-07-31
Support Year
8
Fiscal Year
1998
Total Cost
Indirect Cost
Kotamraju, S; Hogg, N; Joseph, J et al. (2001) Inhibition of oxidized low-density lipoprotein-induced apoptosis in endothelial cells by nitric oxide. Peroxyl radical scavenging as an antiapoptotic mechanism. J Biol Chem 276:17316-23
Zhang, H; Joseph, J; Vasquez-Vivar, J et al. (2000) Detection of superoxide anion using an isotopically labeled nitrone spin trap: potential biological applications. FEBS Lett 473:58-62
Shi, Y; Pritchard Jr, K A; Holman, P et al. (2000) Chronic myocardial hypoxia increases nitric oxide synthase and decreases caveolin-3. Free Radic Biol Med 29:695-703
Singh, R J; Hogg, N; Joseph, J et al. (1999) The peroxynitrite generator, SIN-1, becomes a nitric oxide donor in the presence of electron acceptors. Arch Biochem Biophys 361:331-9
Goss, S P; Hogg, N; Kalyanaraman, B (1999) The effect of alpha-tocopherol on the nitration of gamma-tocopherol by peroxynitrite. Arch Biochem Biophys 363:333-40
Singh, R J; Hogg, N; Goss, S P et al. (1999) Mechanism of superoxide dismutase/H(2)O(2)-mediated nitric oxide release from S-nitrosoglutathione--role of glutamate. Arch Biochem Biophys 372:8-15
Goss, S P; Singh, R J; Kalyanaraman, B (1999) Bicarbonate enhances the peroxidase activity of Cu,Zn-superoxide dismutase. Role of carbonate anion radical. J Biol Chem 274:28233-9
Ferguson, E; Hogg, N; Antholine, W E et al. (1999) Characterization of the adduct formed from the reaction between homocysteine thiolactone and low-density lipoprotein: antioxidant implications. Free Radic Biol Med 26:968-77
Hogg, N; Kalyanaraman, B (1999) Nitric oxide and lipid peroxidation. Biochim Biophys Acta 1411:378-84
Goss, S P; Singh, R J; Hogg, N et al. (1999) Reactions of *NO, *NO2 and peroxynitrite in membranes: physiological implications. Free Radic Res 31:597-606

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