Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL047300-05
Application #
2223548
Study Section
Special Emphasis Panel (ZRG7-RNM (01))
Project Start
1991-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Pathology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Srinivasan, Rekha; Marchant, Roger E; Zagorski, Michael G (2004) ABri peptide associated with familial British dementia forms annular and ring-like protofibrillar structures. Amyloid 11:10-3
Srinivasan, Rekha; Jones, Eric M; Liu, Keqian et al. (2003) pH-dependent amyloid and protofibril formation by the ABri peptide of familial British dementia. J Mol Biol 333:1003-23
Hou, Liming; Kang, Inkyung; Marchant, Roger E et al. (2002) Methionine 35 oxidation reduces fibril assembly of the amyloid abeta-(1-42) peptide of Alzheimer's disease. J Biol Chem 277:40173-6
Shive, M S; Salloum, M L; Anderson, J M (2000) Shear stress-induced apoptosis of adherent neutrophils: a mechanism for persistence of cardiovascular device infections. Proc Natl Acad Sci U S A 97:6710-5
Vacheethasanee, K; Marchant, R E (2000) Surfactant polymers designed to suppress bacterial (Staphylococcus epidermidis) adhesion on biomaterials. J Biomed Mater Res 50:302-12
Kao, W J (2000) Evaluation of leukocyte adhesion on polyurethanes: the effects of shear stress and blood proteins. Biomaterials 21:2295-303
Kao, W J (1999) Evaluation of protein-modulated macrophage behavior on biomaterials: designing biomimetic materials for cellular engineering. Biomaterials 20:2213-21
Shive, M S; Hasan, S M; Anderson, J M (1999) Shear stress effects on bacterial adhesion, leukocyte adhesion, and leukocyte oxidative capacity on a polyetherurethane. J Biomed Mater Res 46:511-9
Vacheethasanee, K; Temenoff, J S; Higashi, J M et al. (1998) Bacterial surface properties of clinically isolated Staphylococcus epidermidis strains determine adhesion on polyethylene. J Biomed Mater Res 42:425-32
Merritt, K; Gaind, A; Anderson, J M (1998) Detection of bacterial adherence on biomedical polymers. J Biomed Mater Res 39:415-22

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