Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL048072-04
Application #
2224128
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1993-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
4
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Akron
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Akron
State
OH
Country
United States
Zip Code
44325
Toot, Jonathan; Dunphy, Gail; Turner, Monte et al. (2004) The SHR Y-chromosome increases testosterone and aggression, but decreases serotonin as compared to the WKY Y-chromosome in the rat model. Behav Genet 34:515-24
Caplea, Ann; Seachrist, Darcie; Daneshvar, Hamid et al. (2002) Noradrenergic content and turnover rate in kidney and heart shows gender and strain differences. J Appl Physiol 92:567-71
Caplea, A; Seachrist, D; Dunphy, G et al. (2001) Sodium-induced rise in blood pressure is suppressed by androgen receptor blockade. Am J Physiol Heart Circ Physiol 280:H1793-801
Ely, D; Turner, M; Milsted, A (2000) Review of the Y chromosome and hypertension. Braz J Med Biol Res 33:679-91
Neves, L A; Santos, R A; Khosla, M C et al. (2000) Angiotensin-(1-7) regulates the levels of angiotensin II receptor subtype AT1 mRNA differentially in a strain-specific fashion. Regul Pept 95:99-107
Valigora, S D; Lib, P K; Dunphy, G et al. (2000) Steroid sulfatase inhibitor alters blood pressure and steroid profiles in hypertensive rats. J Steroid Biochem Mol Biol 73:113-22
Seachrist, D; Dunphy, G; Daneshvar, H et al. (2000) Testosterone increases blood pressure and cardiovascular and renal pathology in spontaneously hypertensive rats. Blood Press 9:227-38
Caplea, A; Seachrist, D; Dunphy, G et al. (2000) SHR Y chromosome enhances the nocturnal blood pressure in socially interacting rats. Am J Physiol Heart Circ Physiol 279:H58-66
Dumas, P; Pausova, Z; Kren, V et al. (2000) Contribution of autosomal loci and the Y chromosome to the stress response in rats. Hypertension 35:568-73
Ely, D; Herman, M; Ely, L et al. (2000) Sodium intake is increased by social stress and the Y chromosome and reduced by clonidine. Am J Physiol Regul Integr Comp Physiol 278:R407-12

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