Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL048308-03
Application #
2224379
Study Section
Medical Biochemistry Study Section (MEDB)
Project Start
1994-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Tennessee Health Science Center
Department
Pharmacology
Type
Schools of Medicine
DUNS #
941884009
City
Memphis
State
TN
Country
United States
Zip Code
38163
Ongur, Dost; Pohlman, Jessica; Dow, Antonia L et al. (2007) Electroconvulsive seizures stimulate glial proliferation and reduce expression of Sprouty2 within the prefrontal cortex of rats. Biol Psychiatry 62:505-12
Edwin, Francis; Wiepz, Gregory J; Singh, Rakesh et al. (2006) A historical perspective of the EGF receptor and related systems. Methods Mol Biol 327:1-24
Wiepz, Gregory J; Edwin, Francis; Patel, Tarun et al. (2006) Methods for determining the proliferation of cells in response to EGFR ligands. Methods Mol Biol 327:179-87
Zhang, Chunxiang; Chaturvedi, Deepti; Jaggar, Laura et al. (2005) Regulation of vascular smooth muscle cell proliferation and migration by human sprouty 2. Arterioscler Thromb Vasc Biol 25:533-8
Poppleton, Helen M; Edwin, Francis; Jaggar, Laura et al. (2004) Sprouty regulates cell migration by inhibiting the activation of Rac1 GTPase. Biochem Biophys Res Commun 323:98-103
Patel, Tarun B (2004) Single transmembrane spanning heterotrimeric g protein-coupled receptors and their signaling cascades. Pharmacol Rev 56:371-85
Deng, Wenlin; Poppleton, Helen; Yasuda, Satoshi et al. (2004) Optimal lysophosphatidic acid-induced DNA synthesis and cell migration but not survival require intact autophosphorylation sites of the epidermal growth factor receptor. J Biol Chem 279:47871-80
Yigzaw, Yinges; Poppleton, Helen M; Sreejayan, Nair et al. (2003) Protein-tyrosine phosphatase-1B (PTP1B) mediates the anti-migratory actions of Sprouty. J Biol Chem 278:284-8
Yang, Huaitao; Scholich, Klaus; Poser, Steve et al. (2002) Developmental expression of PAM (protein associated with MYC) in the rodent brain. Brain Res Dev Brain Res 136:35-42
Yigzaw, Y; Cartin, L; Pierre, S et al. (2001) The C terminus of sprouty is important for modulation of cellular migration and proliferation. J Biol Chem 276:22742-7

Showing the most recent 10 out of 26 publications