Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL048342-05
Application #
2224415
Study Section
Special Emphasis Panel (SRC (FJ))
Project Start
1992-04-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Indiana University-Purdue University at Indianapolis
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
005436803
City
Indianapolis
State
IN
Country
United States
Zip Code
46202
Srivastava, Arun (2004) Gene delivery to human and murine primitive hematopoietic stem and progenitor cells by AAV2 vectors. Methods Mol Biol 246:245-54
Srivastava, Arun (2002) Obstacles to human hematopoietic stem cell transduction by recombinant adeno-associated virus 2 vectors. J Cell Biochem Suppl 38:39-45
Weigel-Kelley, Kirsten A; Srivastava, Arun (2002) Recombinant human parvovirus B19 vectors. Pathol Biol (Paris) 50:295-306
Tan, M; Qing, K; Zhou, S et al. (2001) Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted long-term expression of the human beta-globin gene in hematopoietic cells from homozygous beta-thalassemic mice. Mol Ther 3:940-6
Srivastava, A (2001) Parvovirus vectors for human gene therapy. Curr Opin Mol Ther 3:491-6
Srivastava, A; Kurpad, C; Yoder, M C (2000) Erythroviruses as gene transfer vehicles. Contrib Microbiol 4:133-48
Kurpad, C; Mukherjee, P; Wang, X S et al. (1999) Adeno-associated virus 2-mediated transduction and erythroid lineage-restricted expression from parvovirus B19p6 promoter in primary human hematopoietic progenitor cells. J Hematother Stem Cell Res 8:585-92
Qing, K; Mah, C; Hansen, J et al. (1999) Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nat Med 5:71-7
Qing, K; Khuntirat, B; Mah, C et al. (1998) Adeno-associated virus type 2-mediated gene transfer: correlation of tyrosine phosphorylation of the cellular single-stranded D sequence-binding protein with transgene expression in human cells in vitro and murine tissues in vivo. J Virol 72:1593-9
Wang, X S; Srivastava, A (1998) Rescue and autonomous replication of adeno-associated virus type 2 genomes containing Rep-binding site mutations in the viral p5 promoter. J Virol 72:4811-8

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